Obstructive Lung Diseases |

Association of Health-Related Quality of Life With Disease Severity in Patients With Chronic Obstructive Pulmonary Disease FREE TO VIEW

Kiuk Kim, MD; Eun Jung Cho, MD; Mi Hyun Kim, MD; Woo Hyun Cho, MD; Doo Soo Jeon, MD; Yun Seong Kim, MD; Min Ki Lee, MD
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PNUH, Busan, Republic of Korea

Chest. 2013;144(4_MeetingAbstracts):720A. doi:10.1378/chest.1691396
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SESSION TITLE: COPD Severity Metrics

SESSION TYPE: Original Investigation Slide

PRESENTED ON: Sunday, October 27, 2013 at 03:00 PM - 04:00 PM

PURPOSE: Patients with chronic obstructive pulmonary disease (COPD), which is predicted to be the third most common cause of deaths worldwide by 2020, experience significant impairment in their quality of life (QOL). This study aimed to assess the association of health-related quality of life (HRQL) with disease severity according to the body mass index, degree of airflow obstruction, dyspnea, and exercise capacity (BODE) index in Korean patients with COPD.

METHODS: This was a multicenter prospective cross-sectional study of 245 Korean patients with stable COPD. At enrollment, all patients completed the St George's Respiratory Questionnaire (SGRQ) and Medical outcomes short form-36 (SF-36). The Spearman correlation coefficient (r) was calculated to assess the association between health status scores and clinical or functional variables.

RESULTS: Categorizing the BODE scores into four stages, we found that higher BODE stages were associated with higher (worse) SGRQ scores. The differences among the BODE stages in health status indexes were significant for total SGRQ as well as all three of the SGRQ subscales. In all sections of the SGRQ, scores were moderately to strongly associated with the BODE stages (r=0.25~0.65). The association between SF-36 and the BODE index was significant (p < 0.001).

CONCLUSIONS: HRQOL was associated with disease severity according to the BODE stage in a large Korean population of COPD patients.

CLINICAL IMPLICATIONS: BODE stage is useful for predicting the worsening of HRQL in COPD patients, which suggest action should be taken to support especially in advanced COPD patients.

DISCLOSURE: The following authors have nothing to disclose: Kiuk Kim, Eun Jung Cho, Mi Hyun Kim, Woo Hyun Cho, Doo Soo Jeon, Yun Seong Kim, Min Ki Lee

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