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Postgraduate Education Corner: Pulmonary, Critical Care, and Sleep Pearls |

A 62-Year-Old Man With Hypotension, Hyperkalemia, and HyponatremiaAdrenal Hemorrhage in Antiphospholipid Syndrome

Khalid Mohammad, MD; Nutan Bhaskar, MD; Thaddeus Bartter, MD, FCCP; Manish Joshi, MD, FCCP
Author and Funding Information

From the Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, University of Arkansas for Medical Sciences, Little Rock, AR.

Correspondence to: Khalid Mohammad, MD, University of Arkansas for the Medical Sciences, 4301 W Markham St, Slot #555, Little Rock, AR 72205; e-mail: kmohammad@uams.edu


Reproduction of this article is prohibited without written permission from the American College of Chest Physicians. See online for more details.


Chest. 2013;143(6):1822-1825. doi:10.1378/chest.12-2576
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Reproduction of this article is prohibited without written permission from the American College of Chest Physicians. See online for more details.

AshersonRAHughesGR. Recurrent deep vein thrombosis and Addison’s disease in “primary” antiphospholipid syndrome. J Rheumatol. 1989;16(3):378-380.AshersonRAKhamashtaMAOrdi-RosJ. The “primary” antiphospholipid syndrome: major clinical and serological features. Medicine (Baltimore). 1989;68(6):366-374.InamSSidkiKal-MarshedyARJudzewitschR. Addison’s disease, hypertension, renal and hepatic microthrombosis in ‘primary’ antiphospholipid syndrome. Postgrad Med J. 1991;67(786):385-388.Alarcón-SegoviaDPérez-VázquezMEVillaARDrenkardCCabiedesJ. Preliminary classification criteria for the antiphospholipid syndrome within systemic lupus erythematosus. Semin Arthritis Rheum. 1992;21(5):275-286.AmesDEAshersonRAAyresB. Bilateral adrenal infarction, hypoadrenalism and sphincter hemorrhages in the “primary” antiphospholipid syndrome. Br J Rheumatol. 1992;31(2):117-120.KawashimaASandlerCMErnstRD. Imaging of nontraumatic hemorrhage of the adrenal gland. Radiographics. 1999;19(4):949-963.KovacsKALamYMPaterJL. Bilateral massive adrenal hemorrhage. Assessment of putative risk factors by the case-control method. Medicine (Baltimore). 2001;80(1):45-53.VellaANippoldtTBMorrisJCIII. Adrenal hemorrhage: a 25-year experience at the Mayo Clinic. Mayo Clin Proc. 2001;76(2):161-168.ArltWAllolioB. Adrenal insufficiency. Lancet. 2003;361(9372):1881-1893.EspinosaGSantosECerveraR. Adrenal involvement in the antiphospholipid syndrome: clinical and immunologic characteristics of 86 patients. Medicine (Baltimore). 2003;82(2):106-118.

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