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Diagnosis and Management of Lung Cancer, 3rd ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines Online Only Articles |

Complementary Therapies and Integrative Medicine in Lung CancerComplementary Therapies and Integrative Medicine: Diagnosis and Management of Lung Cancer, 3rd ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines

Gary E. Deng, MD, PhD; Sarah M. Rausch, PhD; Lee W. Jones, PhD; Amitabh Gulati, MD; Nagi B. Kumar, PhD, RD; Heather Greenlee, ND, PhD; M. Catherine Pietanza, MD; Barrie R. Cassileth, PhD, FCCP
Author and Funding Information

From Memorial Sloan-Kettering Cancer Center (Drs Deng, Gulati, Pietanza, and Cassileth), New York, NY; University of Florida College of Medicine (Dr Rausch), Jacksonville, FL; Moffitt Cancer Center and Research Institute (Dr Kumar), Tampa, FL; Duke Cancer Institute (Dr Jones), Durham, NC; and Columbia University (Dr Greenlee), New York, NY.

Correspondence to: Gary E. Deng, MD, PhD, Memorial Sloan-Kettering Cancer Center, 1429 First Ave, New York, NY 10021; e-mail: dengg@mskcc.org


Funding/Sponsors: The overall process for the development of these guidelines, including matters pertaining to funding and conflicts of interest, are described in the methodology article.1 The development of this guideline was supported primarily by the American College of Chest Physicians. The lung cancer guidelines conference was supported in part by a grant from the Lung Cancer Research Foundation. The publication and dissemination of the guidelines was supported in part by a 2009 independent educational grant from Boehringer Ingelheim Pharmaceuticals, Inc.

COI Grids reflecting the conflicts of interest that were current as of the date of the conference and voting are posted in the online supplementary materials.

Disclaimer: American College of Chest Physician guidelines are intended for general information only, are not medical advice, and do not replace professional medical care and physician advice, which always should be sought for any medical condition. The complete disclaimer for this guideline can be accessed at http://dx.doi.org/10.1378/chest.1435S1.

Reproduction of this article is prohibited without written permission from the American College of Chest Physicians. See online for more details.


Chest. 2013;143(5_suppl):e420S-e436S. doi:10.1378/chest.12-2364
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Background:  Physicians are often asked about complementary therapies by patients with cancer, and data show that the interest in and use of these therapies among patients with cancer is common. Therefore, it is important to assess the current evidence base on the benefits and risks of complementary therapies (modalities not historically used in modern Western medicine).

Methods:  A systematic literature review was carried out and recommendations were made according to the American College of Chest Physicians Evidence-Based Clinical Practice Guidelines development methodology.

Results:  A large number of randomized controlled trials, systematic reviews, and meta-analyses, as well as a number of prospective cohort studies, met the predetermined inclusion criteria. These trials addressed many different issues pertaining to patients with lung cancer, such as symptoms of anxiety, mood disturbance, pain, quality of life, and treatment-related side effects. The available data cover a variety of interventions, including acupuncture, nutrition, mind-body therapies, exercise, and massage. The body of evidence supports a series of recommendations. An evidenced-based approach to modern cancer care should integrate complementary therapies with standard cancer therapies such as surgery, radiation, chemotherapy, and best supportive care measures.

Conclusions:  Several complementary therapy modalities can be helpful in improving the overall care of patients with lung cancer.


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