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Correspondence |

Significance of Lymphadenopathy in IgG4-Related Sclerosing Disease and SarcoidosisIgG4-related Sclerosing Disease and Sarcoidosis FREE TO VIEW

Narat Srivali, MD; Supawat Ratanapo, MD; Patompong Ungprasert, MD; Wisit Cheungpasitporn, MD
Author and Funding Information

From the Department of Medicine, Bassett Medical Center.

Correspondence to: Wisit Cheungpasitporn, MD, 1 Atwell Rd, Cooperstown, NY 13326; e-mail: wisit.cheungpasitporn@bassett.org


Financial/nonfinancial disclosures: The authors have reported to CHEST that no potential conflicts of interest exist with any companies/organizations whose products or services may be discussed in this article.

Reproduction of this article is prohibited without written permission from the American College of Chest Physicians. See online for more details.


Chest. 2013;143(4):1191-1192. doi:10.1378/chest.12-2954
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To the Editor:

We read with interest the recent article in CHEST (November 2012) by Rho et al.1 The authors presented an interesting case of IgG4-related sclerosing disease.

We were wondering whether there was any significant lymphadenopathy. Asymptomatic IgG4-related lymphadenopathy is common, occurring in 80% of patients with autoimmune pancreatitis.2 Cough and dyspnea could be clinical manifestations of pulmonary sarcoidosis. Also, lymphadenopathy and pulmonary nodules are common in sarcoidosis. Interestingly, there was a biopsy specimen-proven report of the association between IgG4-related disease and sarcoidosis.3 This association is fascinating and we may have overlooked the diagnosis of IgG4-related sclerosing disease in the past in patients with or without sarcoidosis.

References

Rho BH, Qama D, Choi W-I, Kwon KY. A 61-year-old man with dyspnea. Chest. 2012;142(5):1344-1347. [CrossRef] [PubMed]
 
Hamano H, Arakura N, Muraki T, Ozaki Y, Kiyosawa K, Kawa S. Prevalence and distribution of extrapancreatic lesions complicating autoimmune pancreatitis. J Gastroenterol. 2006;41(12):1197-1205. [CrossRef] [PubMed]
 
Michel L, Clairand R, Néel A, Masseau A, Frampas E, Hamidou M. Association of IgG4-related disease and sarcoidosis. Thorax. 2011;66(10):920-921. [CrossRef] [PubMed]
 

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References

Rho BH, Qama D, Choi W-I, Kwon KY. A 61-year-old man with dyspnea. Chest. 2012;142(5):1344-1347. [CrossRef] [PubMed]
 
Hamano H, Arakura N, Muraki T, Ozaki Y, Kiyosawa K, Kawa S. Prevalence and distribution of extrapancreatic lesions complicating autoimmune pancreatitis. J Gastroenterol. 2006;41(12):1197-1205. [CrossRef] [PubMed]
 
Michel L, Clairand R, Néel A, Masseau A, Frampas E, Hamidou M. Association of IgG4-related disease and sarcoidosis. Thorax. 2011;66(10):920-921. [CrossRef] [PubMed]
 
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