A 34-year-old woman with Fanconi anemia and incontinentia pigmenti was seen for a reassessment of asthma, postnasal drip, and cough that were being treated with prednisone, budesonide, and formoterol and montelukast. She had clinical allergies to cat and grass pollen (confirmed on skin-prick testing, but normal total serum IgE) and had never smoked. She had asthma from childhood with symptoms of episodic wheezing, cough, and breathlessness on exertion that were quickly relieved by short-acting bronchodilators, and she had been under the care of two respirologists who had confirmed variable airflow obstruction by demonstrating significant diurnal peak flow variability of >20% over a 2-week observation period. She had a history of several hospitalizations due to febrile neutropenia and recurrent infections, and, therefore, had been started on regular injections of filgrastim, a granulocyte colony-stimulating factor (G-CSF) analog. Recently, she had been diagnosed with oropharyngeal cancer that was treated by local excision. An autofluorescence bronchoscopic evaluation did not show any evidence of in situ cancer of the airway epithelium.