We used a 24-question survey. Twelve questions assessed demographics, such as age, sex, education level, and baseline health. Twelve questions assessed patient knowledge of genetics, inheritance, reproduction, and health concerns for patients with CF wanting to reproduce. We then provided each patient (N =40) with a trifold, color brochure addressing these topics and reassessed patient knowledge with patients able to reference the brochure. All study protocols and materials were approved by The University of Alabama (UAB) Institutional Review Board (Protocol X100704010).