Prophetically, Dr Petty had been telling us all along that when it comes to sedative agent choice, a correct option may be little to no sedative drug at all. This approach may apply to more patients than we imagine. Yet, as mentioned at the outset, sedative infusion use seems to be on the increase. Reversing this trend may require further investigation and the use of multidisciplinary, nursing-implemented protocols that have been effective in improving outcomes. Future clinical trials or individual ICU benchmarking strategies should involve national or local multidisciplinary experts, respectively, to determine which protocolized approaches best optimize all parts of the animated strategy. They would likely use sedation scales, delirium monitoring and therapy, and mobilization strategies, with the ultimate goal of more aggressively identifying those who do not require continuous sedative drug administration.