SESSION TYPE: Respiratory Infections Posters II
PRESENTED ON: Wednesday, October 24, 2012 at 01:30 PM - 02:30 PM
PURPOSE: To evaluate the efficacy and safety of Chinese herb named Jinhuaqinggankeli(JHQG) in treating seasonal influenza.
METHODS: This is a prospective, double- blinded, randomized, placebo-controlled trial included six hospitals from China. Patients who met the seasonal influenza diagnosis and had fever more than 38.3 degree were randomly assigned to take either Jinhuaqinggan decoction (composed of 12 Chinese herbal medicines, including honey-fried Herba Ephedrae) or placebo controls four times daily for 5 days. The primary outcome was time to fever resolution.
RESULTS: A total of 86 patients enrolled in the study and 44 patients got JHQG treatment. A significant reduction in the estimated median time to fever resolution compared to the placebo control group. (25.8 hours [95%CI, 14.5 to 35.0 ] vs. 39.8 hours [95% CI, 29.0 to 51.5]; P < 0.001). The change of symptom scores in the Chinese herb treatment group is significantly different from the placebo controls (P = 0.007). Two patients who received JHQG reported nausea.
CONCLUSIONS: Chinese herb named JHQG could reduce time to fever resolution in patients with seasonal influenza virus infection.
CLINICAL IMPLICATIONS: These data suggest that Chinese herb might serve as alternative treatment for seasonal influenza.
DISCLOSURE: The following authors have nothing to disclose: Zaiya Jin, Yongjun Bian, Zhiguo Liu, Lei Li, Guangxi Li, Hui Li, Guoqin Li
No Product/Research Disclosure InformationGuang An Men Hospital, China Academy of Chinese Medical Science, Beijing, China