SESSION TYPE: Non Pulmonary Critical Care Posters
PRESENTED ON: Wednesday, October 24, 2012 at 01:30 PM - 02:30 PM
PURPOSE: To compare outcome of patients suffered from AKI due to septic and non-septic etiology.
METHODS: Patients admitted to our ICU between march 2010 to march 2012 ,screened for AKI using RIFLE criteria , grade I (RISK), II (INJURY) , III (FAILURE) and divided into two groups as septic and non-septic etiologies. Two groups were compared using -mean age, icu stay , need of hemodialysis / RRT ,refractory pulmonary edema , metabolic acidosis ,uremic encephalopathy , hyperkalemia , (MODS) multiorgan dysfunction and mortality. Statistical analysis done using SPSS version 16 with mean ,standard deviation , z score ,chi-square test and multivariate analysis.
RESULTS: patients in the septic group had statistically significant increased icu stay , need of RRT, incidence of refractory acidosis , hyperkalemia ,uremic encephalopathy and mortality .
CONCLUSIONS: Even though the criteria to diagnose AKI is equally sensitive for both sepsis and non-sepsis etiology , patients in the sepsis group deteriorated more rapidly ,had higher incidence of life threatening complications and mortality.They had higher average icu stay and increased cost of treatment.
CLINICAL IMPLICATIONS: Tight screening for sepsis related AKI and more aggressive management is required .Early hemodialysis / RRT should be initiated rather than awaiting for complications to occur. This will definitely reduce the burden of sepsis related in hospital mortality and expenses.
DISCLOSURE: The following authors have nothing to disclose: Prakash Gore, Sanjay Srivastava
No Product/Research Disclosure InformationTata Motors Hospital., Jamshedpur, India