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Pulmonology Procedures |

The Efficacy and Safety of Interventional Bronchoscopic Techniques in the Management of Benign Airway Stenosis

Nan Li, MD; Guangfa Wang*, MD; Ying Zhou, MD; Wei Zhang, MD; Hong Zhang, MD
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Peking University First Hospital, Division of Pulmonary and Critic Care Medicine, Beijing, China


Chest. 2012;142(4_MeetingAbstracts):913A. doi:10.1378/chest.1389114
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Abstract

SESSION TYPE: Bronchoscopy and Interventional Procedures Posters

PRESENTED ON: Wednesday, October 24, 2012 at 01:30 PM - 02:30 PM

PURPOSE: Interventional bronchoscopy is one of the modalities for treatment of benign airway stenosis. Our work is to analyze the efficacy and safety of multiple bronchoscopic techniques basing on balloon dilation combined with cryotherapy treating benign proximal airway stenosis.

METHODS: Patients with benign tracheobronchial stenosis were included and analyzed retrospectively. Two experienced interventional experts compared the degree of airway stenosis before and after bronchoscopic therapy. Follow-up by telephone were completed to evaluate MRC dyspnea scale. Airway stenosis degree, MRC dyspnea scale and procedure-related complications were compared.

RESULTS: From January 2007 to March 2011, 44 patients (24 males, 20 females, 49.9+/-17.9y) with 50 benign proximal airway stenosis locations received 165 endoscopic procedures (mean of 3 (1, 19) per patient) in our department, including balloon dilation, cryotherapy , electrocautery, metal stent placement and intermittently corticosteroid local injection. 6 patients can’t be contacted by phone. 5 patients died unrelated with interventional procedure and airway stenosis during the follow-up. Airway stenosis was immediately relieved after all the techniques. Comparing with the stenosis degree before treatment, airway diameter were significantly increased through sequential bronchoscopic treatments (P<0.05). 67.78% (27/39) of patients were cured within 90 days, 82.05% (32/39) of patients finished treatments within 180 days. 25 patients complaining dyspnea completed telephone followed-up at 363 (27,1552) days after last treatment. The MRC dyspnea scale was improved from 3(1, 5) before treatment to 0(1, 5) with effective rate of 96% (P=0.002). No severe complications occurred in peroperative period of endoscopic procedures.

CONCLUSIONS: Sequential endoscopic therapy mainly basing on balloon dilation and/or cryotherapy was an effective and safe treatment on benign proximal airway stenosis, which can improve quality of life, should be considered one of the main managements.

CLINICAL IMPLICATIONS: Sequential endoscopic therapy should be considered one of the main managements for benign central airway stenosis.

DISCLOSURE: The following authors have nothing to disclose: Nan Li, Guangfa Wang, YIng Zhou, Wei Zhang, Hong Zhang

No Product/Research Disclosure Information

Peking University First Hospital, Division of Pulmonary and Critic Care Medicine, Beijing, China

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