SESSION TYPE: Outcomes/Quality Control Posters
PRESENTED ON: Wednesday, October 24, 2012 at 01:30 PM - 02:30 PM
PURPOSE: Increased oxygen debt is associated with increased mortality in critically ill patients. Central Venous Oxygen Saturation has been used as a surrogate for oxygen debt and has been useful as a target for resuscitation of critically ill patients. SIR Sis being used to identify clinically at risk population for critical illness. However no good correlation data has evaluated the association between SIRS and oxygen debt.
METHODS: We retrospectively evaluated data from 80 critically ill patients from an inner city hospital. From these patients we obtained 168 complete data sets comparing ScVO2 and SIRS criteria. One-way Analysis of Variance (ANOVA) was performed comparing SIRS overall and each individual category to oxygen debt. The data was subsequently separated with regard to heart rate and respiratory rate. With regard to heart rate into patients on/off beta-blockers, with respiratory rate, patients on/off ventilator support. Oxygen debt was defined as ScVO2 less than 70%.
RESULTS: The correlation of data reflected an association between oxygen debt (ScVO2 less than 70%) and positive temperature criteria for SIRS. The ScVO2 mean when the temperature criterion was met was 66.49 (+/-) 3.69 versus 73.36 (+/-) 1.19 when the temperature criterion was not met *p=0.021. However, all of the other SIRS criteria failed to show any correlation.
CONCLUSIONS: Temperature (criteria of SIRS) correlates with and should be considered with greater concern (than other SIRS criteria) with regard to oxygen debt.
CLINICAL IMPLICATIONS: Understanding the relationship between systemic inflammation and oxygen debt could have profound implications in the management of critically ill patients.
DISCLOSURE: The following authors have nothing to disclose: Gerard Baltazar, Krishna Akella, Imitiaz Ahmed, Akella Chendrasekhar
No Product/Research Disclosure InformationWyckoff Heights Medical Center, Brooklyn, NY