Cardiovascular Disease |

The Usefulness of B-Type Natriuretic Peptide in the Early Diagnosis of Right Ventricular Infarction FREE TO VIEW

Hyeon Gook Lee*, PhD; Kiuk Kim, PhD; Byung-Jae Ahn, PhD
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MMC, Busan, Republic of Korea

Chest. 2012;142(4_MeetingAbstracts):87A. doi:10.1378/chest.1388331
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SESSION TYPE: Arrhythmia and Coronary Artery Disease

PRESENTED ON: Monday, October 22, 2012 at 11:15 AM - 12:30 PM

PURPOSE: 19-51% of inferior acute myocardial infarction(AMI) patients combine with right ventricular infarction(RVI). RVI is associated with a highly increased in-hospital mortality. Therefore, early diagnosis of RVI in inferior acute myocardial infarction is very important. This study was planned to investigate the usefulness of B-type natriuretic peptide(BNP) in the early diagnosis of RVI.

METHODS: The patients who were diagnosed as inferior AMI and primary coronary intervention done within 6 hours were selected for this study. The subject patients(n=100) had a significant luminal narrowing at right coronary artery, and no specific findings in left coronary artery on coronary angiograms. The patients were divided into group A for those who had a proximal lesion and RVI, group B with a proximal lesion but without RVI, and group C with a distal lesion.

RESULTS: Twenty eight of the 100 subject patients suffered from RVI. Among 72 patients who did not accompany with RVI, 26(36%) had a significant stenosis in their proximal portion while 46(64%) had a significant distal stenosis. The level of BNP was 298.8±138.5 pg/mL in group A(n=28), 83.2±53.6 pg/mL in group B(n=26), and 68.1±46.9 pg/mL in group C(n=46) respectively. BNP was increased when RVI was accompanied regardless of the site of the lesion.

CONCLUSIONS: BNP is a useful marker for diagnosis of combined RVI in case of inferior AMI.

CLINICAL IMPLICATIONS: BNP is a useful marker for diagnosis of combined RVI in case of inferior AMI.

DISCLOSURE: The following authors have nothing to disclose: Hyeon Gook Lee, Kiuk Kim, Byung-Jae Ahn

No Product/Research Disclosure Information

MMC, Busan, Republic of Korea




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