0
Diffuse Lung Disease |

Airway Hyperresponsiveness in Patients With Bronchiectasis

Jamsak Tscheikuna*, MD
Author and Funding Information

Mahidol University, Bangkok, Thailand


Chest. 2012;142(4_MeetingAbstracts):428A. doi:10.1378/chest.1387303
Text Size: A A A
Published online

Abstract

SESSION TYPE: Cystic Fibrosis/ Bronchiectasis Posters

PRESENTED ON: Wednesday, October 24, 2012 at 01:30 PM - 02:30 PM

PURPOSE: Bronchiectasis is a chronic lung disease and commonly found in the patients with chronic cough. This disease caused chronic pulmonary infection, impaired pulmonary function, and increased morbidity and mortality. Prevalences of airway hyperresponsiveness(AHR) in bronchiectatic patients are vary between studies. This study aims to determine the prevalence and predictors of airway hyperresponsiveness in patients with bronchiectasis.

METHODS: A cross-sectional study was performed to evaluate 33 bronchiectatic patients between May 2010 and December 2010. Demographic data including sex, age, smoking status, occupation, co-morbid diseases, underlying lung diseases, clinical features, radiographic findings, and treatments were analyzed. Methacholine challenge test(MCT), pulmonary function test and exhaled nitric oxide(NO) were measured.

RESULTS: The prevalence of AHR was 18% (6 of 33 patients). Their exhaled NO levels were all in normal limit. There was no correlation between MCT and exhaled NO level, also between airway responsiveness and demographic data predictors.

CONCLUSIONS: Prevalence of AHR in bronchiectatic patients was higher than general adult population. Mechanism of AHR in bronchietasis may be different from in asthma and no predictor was found in this study.

CLINICAL IMPLICATIONS: The use of bronchodilator may be benefit in some patients with bronchiectasis but the use of inhale steroid may not indicate.

DISCLOSURE: The following authors have nothing to disclose: Jamsak Tscheikuna

No Product/Research Disclosure Information

Mahidol University, Bangkok, Thailand

Sign In to Access Full Content

MEMBER & INDIVIDUAL SUBSCRIBER

Want Access?

NEW TO CHEST?

Become a CHEST member and receive a FREE subscription as a benefit of membership.

Individuals can purchase this article on ScienceDirect.

Individuals can purchase a subscription to the journal.

Individuals can purchase a subscription to the journal or buy individual articles.

Learn more about membership or Purchase a Full Subscription.

INSTITUTIONAL ACCESS

Institutional access is now available through ScienceDirect and can be purchased at myelsevier.com.

Sign In to Access Full Content

MEMBER & INDIVIDUAL SUBSCRIBER

Want Access?

NEW TO CHEST?

Become a CHEST member and receive a FREE subscription as a benefit of membership.

Individuals can purchase this article on ScienceDirect.

Individuals can purchase a subscription to the journal.

Individuals can purchase a subscription to the journal or buy individual articles.

Learn more about membership or Purchase a Full Subscription.

INSTITUTIONAL ACCESS

Institutional access is now available through ScienceDirect and can be purchased at myelsevier.com.

Figures

Tables

References

NOTE:
Citing articles are presented as examples only. In non-demo SCM6 implementation, integration with CrossRef’s "Cited By" API will populate this tab (http://www.crossref.org/citedby.html).

Some tools below are only available to our subscribers or users with an online account.

Sign In to Access Full Content

MEMBER & INDIVIDUAL SUBSCRIBER

Want Access?

NEW TO CHEST?

Become a CHEST member and receive a FREE subscription as a benefit of membership.

Individuals can purchase this article on ScienceDirect.

Individuals can purchase a subscription to the journal.

Individuals can purchase a subscription to the journal or buy individual articles.

Learn more about membership or Purchase a Full Subscription.

INSTITUTIONAL ACCESS

Institutional access is now available through ScienceDirect and can be purchased at myelsevier.com.

Related Content

Customize your page view by dragging & repositioning the boxes below.

Find Similar Articles
CHEST Journal Articles
PubMed Articles
Bronchiectasis and Aspergillus: How are they linked? Med Mycol Published online Oct 28, 2016;
  • CHEST Journal
    Print ISSN: 0012-3692
    Online ISSN: 1931-3543