Obstructive Lung Diseases |

Comparing Psychometric Performance and Patients' Preference of Two Disease Specific Questionnaires in Patients With Both COPD and Heart Failure FREE TO VIEW

Leola Metzemaekers*, BA; Farida Berkhof, MA; Steven Uil, MA; Jan van den Berg, PhD
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Isala Klinieken Zwolle, Zwolle, Netherlands

Chest. 2012;142(4_MeetingAbstracts):726A. doi:10.1378/chest.1386173
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PRESENTED ON: Wednesday, October 24, 2012 at 01:30 PM - 02:30 PM

PURPOSE: Currently, health status (HS) in patients with both COPD and heart failure is assessed with two or more disease specific questionnaires. To investigate whether this can be reduced, we compared psychometric performance and patient preference of Clinical COPD Questionnaire (CCQ) and Minnesota Living with Heart Failure Questionnaire (MLHF-Q).

METHODS: Internal consistency, concurrent validity, convergent validity, discriminant validity, reproducibility, responsiveness and patient preference were determined. The Short Form-36 (SF-36) was used as external criteria. CCQ, MLHF-Q and SF-36 were completed at the start of the study. After 2 and 12 weeks the questionnaires were repeated, together with a global rating of change instrument. Patient preference was assessed using a self-made questionnaire (SMQ) after 12 weeks.

RESULTS: 38 patients were included. Internal consistency was adequate for the CCQ (Cronbach’s α 0.72 to 0.86) and MLHF-Q (Cronbach’s α 0.84 to 0.89), except CCQ domain symptoms (Cronbach’s α 0.70). Concurrent validity showed significant correlations between corresponding domains of the CCQ and the SF-36 (rs -0.33 to -0.76), except corresponding SF-36 domain role-emotional (rs -0.19, p=0.25). Corresponding domains of the MLHF-Q and SF-36 were also significantly correlated (rs -0.33 to 0.67), except corresponding SF-36 domain pain (rs -0.28, p=0.09). Convergent validity showed strong significant correlations between MLHF-Q and CCQ (rs 0.71 to 0.83), but weak correlations between CCQ domains symptoms and functional with MLHF-Q (rs 0.37 to 0.64). Reliability of CCQ and MLHF-Q in stable patients was high (intraclass correlations coefficients 0.89-0.97 and 0.87-0.93). Bland-Altman plots showed small mean differences for CCQ total -0.03 (±0.34) and MLHF-Q total 0.00 (±10.51), indicating good agreement. Discriminant validity and responsiveness were inconsistent in both questionnaires. Patients appeared to prefer the CCQ.

CONCLUSIONS: CCQ and MLHF-Q were valid and reliable instruments to measure HS in patients with both COPD and heart failure. Based on all results there is a slight preference for the CCQ.

CLINICAL IMPLICATIONS: HS in patients with both COPD and heart failure can be measured with one questionnaire instead of two, preferably the CCQ.

DISCLOSURE: The following authors have nothing to disclose: Leola Metzemaekers, Farida Berkhof, Steven Uil, Jan van den Berg

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Isala Klinieken Zwolle, Zwolle, Netherlands




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