SESSION TYPE: Respiratory Infections Posters I
PRESENTED ON: Wednesday, October 24, 2012 at 01:30 PM - 02:30 PM
PURPOSE: Pulmonary tuberculosis may lead to pulmonary impairment and health loss. The aim of the study was to assess the influence of physical exercise on pulmonary function and quality of life (QoL) in patients diagnosed and treated for pulmonary tuberculosis.
METHODS: We investigated 194 patients who were observed in local dispensary after treatment for pulmonary tuberculosis was completed. All the patients were divided into active group (if they in their own opinion were taking regular physical exercise during any period of their life) and inactive group. QoL was studied by St. George's Respiratory Questionnaire (SGRQ), and UCSD Shortness of Breath Questionnaire (SOBQ). Pulmonary function was studied by spirometry.
RESULTS: Groups did not differ in age and gender. In patients inactive group (74 patients) and inactive group (120 patients), respectively, FVC were 97,3±20,2% and 100,1±22,3% (p>0.05); FEV1 were 79,6±23,4% and 87,4±25,3% (p<0.05); FEV1/FVC were 0,67±0,14 and 0,71±0,12 (p<0.05); PEF - 72,7±26,4% and 80,0±26,1% (p>0.05); MMEF25-75 - 49,1±28,2% and 61,3±33,2% (p<0.05). Difference in mean FEV1 between groups was 393 ml and difference in mean FVC was 335 ml. In inactive group and in active group, respectively, airway obstruction (FEV1/FVC <0.7) was 54,1% and 41,7% (OR 1.65; CI 95% 0.92 to 2.95; p>0,05). In inactive group and active group low pulmonary function (FEV1<80%) was 43,2% and 32,5% (OR 1.58; CI 95% 0.87 to 2.88; p>0,05). In patients inactive group and inactive group, respectively, Symptoms SGRQ scores were 33,3±27,8% and 24,0±22,9% (difference was 9,3 points; p<0.05); Activity SGRQ scores were 32,8±21,2% and 25,8±23,0% (difference was 7,0 points; p<0.05); Impact SGRQ scores were 19,0±19,3% and 14,4±18,8% (difference was 4,6 points; p>0.05); Total SGRQ scores were 25,4±19,8% and 19,3±19,4% (difference was 6,1 points; p<0.05); SOBQ scores were 15,2±14,2 points and 11,8±14,5 points (difference was 3,4 points; p>0,05).
CONCLUSIONS: QoL and pulmonary function were better in patients who took regular physical exercise during any period of their life.
CLINICAL IMPLICATIONS: Regular physical exercise may prevent pulmonary function and health loss in patients treated for pulmonary tuberculosis.
DISCLOSURE: The following authors have nothing to disclose: Mikhail Chushkin, Sergey Mandrykin, Eduard Tikhokhod, Sergey Smerdin
No Product/Research Disclosure InformationResearch Institute of Phthisiopulmonology, Moscow, Russian Federation