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Lung Cancer |

EBUS in the Differential Diagnosis Between Malignant and Benign Lesions by Two Characteristic Echoic Features

Huang Yu*, MD
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Guangdong Provincial People Hospital, Guangzhou, China


Chest. 2012;142(4_MeetingAbstracts):640A. doi:10.1378/chest.1367100
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Abstract

SESSION TYPE: Lung Cancer Posters II

PRESENTED ON: Wednesday, October 24, 2012 at 01:30 PM - 02:30 PM

PURPOSE: To assess the feasibility of EBUS in the differential diagnosis between malignant and benign lesions by the following two characteristic echoic features indicating malignancy: halo sign;low echoes.

METHODS: EBUS images from 102 patients who undergone bronchoscopy for a peripheral lung lesion were analyzed. The sensitivity and specificity for each echoic feature or in combination in diagnosing malignancy or benignity were determined.

RESULTS: Halo sign and low echoes are two echoic features indicating malignancy. Low echoes has higher sensitivity (89.46%) and specificity (83%) in the diagnosis of malignancy, while halo sign has sensitivity (69.51%) and specificity (65%). The predictive value for the sensitivity of malignancy of a lesion with any one of the two echoic features is 94.6%. The predictive value for the specificity of malignancy of a lesion with both of these two echoic features is 93%.

CONCLUSIONS: These results indicate that EBUS is useful as an adjunct in lung cancer diagnosis, especially when peripheral lung lesions are invisible in traditional bronchoscopy.

CLINICAL IMPLICATIONS: Endobronchial ultrasonography is a safe and practical examinationmethod. It can provide physicians a chance to observe the lesions from inside and discover more information than that obtained through radiology in discriminating peripheral pulmonary lesions.

DISCLOSURE: The following authors have nothing to disclose: Huang Yu

No Product/Research Disclosure Information

Guangdong Provincial People Hospital, Guangzhou, China

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