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Pulmonary Vascular Disease |

Role of Pulmonary Embolism Severity Index in Predicting the Prognosis of Patients With Pulmonary Embolism

Yavuz Havlucu, MD; Aysen Oz, MD; Tugba Goktalay, MD; Aysin Coskun, MD; Pinar Celik, PhD; Arzu Yorgancioglu*, PhD
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Celal Bayar University Medical Faculty, Manisa, Turkey


Chest. 2012;142(4_MeetingAbstracts):854A. doi:10.1378/chest.1364846
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Abstract

SESSION TYPE: DVT/PE/Pulmonary Hypertension Posters II

PRESENTED ON: Wednesday, October 24, 2012 at 01:30 PM - 02:30 PM

PURPOSE: Pulmonary Embolism Severity Index(PESI) that is simple and practical has been shown to be successful risk stratification tool for patients with PE.We aimed to investigate the power of PESI to estimate the prognosis of patients with PE.

METHODS: A retrospective cohort study,patients with acute PE hospitalized at Celal Bayar University Chest Disease Clinic between July 2008-November 2011 were included.Sociodemographic data,physical examination,computerized tomography,echocardigraphy,and doppler ultrasoundgraphy findings,PESI scores(Table1),complication due to treatment,presence of mortality(hospital,30and 90 day),and reason of mortality were recorded.Complication due to treatment and mortality rate were calculated according to each PESI risk class.

RESULTS: 124 patient were included study.There were66 male(53,2%) and mean age was 63±184,9 years.23(18,5) were assigned to PESI class 1,29(20,2%)to PESI class 2,22(17,7%)to PESI class 3,18(14,6%)to PESI class 4,and 36(29%)to PESI class 5.Complication rates due to treatment were 4,3%,13,6%,27,2%,22,2%,and 41,6%respectively(p=0,01).Overall mortality rate was 18,5%,mortality due to PE was 8,8%,and mortality due to other than PE was 9,6%.Total mortality rates in class 1,2,and 3 were 0%,but in class 4 it was 11,1% and in class 5 it was 58,3%(p<0,000).This difference also seen accorrding to mortality causes.When the comparison of mortality time with mortality cause was done,the reason of mortality during hospitalization was PE and the reason of mortality after hospitalization was due to other than PE(p=0,01).When the PESI score is accepted as 115 to predict overall mortality,the sensitivity is 95% and specifity is 82%.

CONCLUSIONS: PESI score was found to be significantly correlated with hospital,30,and 90-day mortality and complications due to treatment.

CLINICAL IMPLICATIONS: PESI can be used to predict the prognosis of patients with PE.

DISCLOSURE: The following authors have nothing to disclose: Yavuz Havlucu, Aysen Oz, Tugba Goktalay, Aysin Coskun, Pinar Celik, Arzu Yorgancioglu

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Celal Bayar University Medical Faculty, Manisa, Turkey

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