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A Study of Clinical Profile and Treatment Outcome of DOTS (Directly Observed Therapy Short Course) Regime in 250 Pulmonary and Extrapulmonary Tuberculosis Patients in Hamidia Hospital, Bhopal in the Year 2011 FREE TO VIEW

Abhishek Gaikwad*, MD; Kuldeep Deopujari, MD
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Gandhi Medical College and Hamidia Hospital, Bhopal, Bhopal, India

Chest. 2012;142(4_MeetingAbstracts):198A. doi:10.1378/chest.1353162
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SESSION TYPE: Respiratory Infections Posters I

PRESENTED ON: Wednesday, October 24, 2012 at 01:30 PM - 02:30 PM

PURPOSE: To study clinical profile of patients and to evaluate the effectiveness of DOTS regime in the terms of cure rate, failure rate,defaulter rate and deaths.

METHODS: 250 newly diagnosed patients having pulmonary or extra pulmonary Tuberculosis who are attending the DOTS centre at HAMIDIA. Hospital,BHOPAL in year 2011 and fulfilling the inclusion and exclusion criteria were included.Their clinical profile was studied and treatment outcome was observed in them after treatment.

RESULTS: Pulmonary tuberculosis cases predominated 175 (70%) cases,extra pulmonary cases accounted for 75 (30%) ,highest incidence of tuberculosis was observed in the age group 21-40 years-125 patients (50%),most common symptom was cough and weight loss 192 cases(76.7%) ,most common finding on examination was pallor 170 patients (68%), most common x ray finding was unilateral consolidation 77(32%) patients. Sputum conversion rate at end of intensive phase was 89.33% while at end of extended intensive phase,2nd mth of continuation phase and at end of treatment was 92%.So at end of treatment among175 pulmonary tuberculosis patients cure rate was 77.71% i.e136 patients, failure rate was 5.14%-9 patients, defaulter rate was 4.%-7 patients, death rate was 4.57%..-8 and patients declared completed treatment. were 8.57%-15patients. Of the 75 extra pulmonary cases 68 Patients (90%) were declared treatment completed 4 patients (5.3%) were defaulters, 3 patient died.

CONCLUSIONS: Directly Observed Treatment is an thus effective intervention for improving adherence to tuberculosis treatment programme in a resource-poor country.

CLINICAL IMPLICATIONS: The problems of treatment noncompliance and resulting drug resistance can be solved by DOTS regime and better success rate can be achieved.

DISCLOSURE: The following authors have nothing to disclose: Abhishek Gaikwad, Kuldeep Deopujari

No Product/Research Disclosure Information

Gandhi Medical College and Hamidia Hospital, Bhopal, Bhopal, India




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