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Editorials |

Emerging Bronchoscopic Therapies for Stage IV Advanced EmphysemaBronchoscopic Therapy Emphysema Lung Transplant

Jim J. Egan, MD
Author and Funding Information

From the National Advanced Lung Disease and Lung Transplantation Program, Mater Misericordiae University Hospital; St Vincent’s University Hospital; Our Lady’s Children’s Hospital; and the National Organ Donation and Transplantation Office, Dr Stevens Hospital.

Correspondence to: Jim J. Egan, MD, Mater Misericordiae University Hospital, Eccles St, Dublin, D7, Ireland; e-mail: jegan@mater.ie


Financial/nonfinancial disclosures: The author has reported to CHEST the following conflicts of interest: Dr Egan has acted as a principal investigator for, and consultant to, Uptake Medical Inc; as a principal investigator for Emphasys Medical Inc; and as a consultant to Forbion Inc.

Reproduction of this article is prohibited without written permission from the American College of Chest Physicians. See online for more details.


Chest. 2012;142(3):552-553. doi:10.1378/chest.12-0596
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Extract

Advanced stage IV emphysema represents a significant burden to patients and their families. It is characterized by disabling breathlessness and unexpected prolonged survival. This results in distressingly poor quality of life resulting from dynamic hyperinflation on exercise and recurrent infective exacerbations. Consequently, many patients seek surgical intervention in the form of lung transplantation and/or volume reduction surgery. Surgical therapy is fraught with difficulty and is particularly dependent on preconditioning with pulmonary rehabilitation. Therefore, pulmonary rehabilitation is the foundation of management on which all other therapies are built at this phase of emphysema.

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