PURPOSE: To investigate the association between obesity, nocturnal oxygen saturation, and pulmonary function data in morbidly obese persons.
METHODS: Thirty-one obese women, mean age 44±11 years,and 17 obese men,mean age, 46±8 years, underwent preoperative nocturnal polysomnography and pulmonary function testing. The mean body mass index (BMI) was 50±8 kg/m2 in women and 55±8 kg/m2 in men (p not significant). Sleep data analyzed included average and lowest nocturnal oxygen saturation. BMI data, expiratory reserve volume (ERV)% data, and functional residual capacity (FRC)% data were also included in the analysis.
RESULTS: Pearson correlation coefficients showed a significant association between ERV% and average oxygen saturation (p=0.027), between BMI and lowest oxygen saturation (p=0.034), and between BMI and average oxygen saturation (p=0.039). The mean age, BMI, ERV%, and FRC% were not significantly different between obese women and men. The lowest oxygen saturation was 80±10% in obese women and 62±19% in obese men (p=0.001). The average oxygen saturation was 88±5% in obese women and 83±6% in obese men (p=0.005).
CONCLUSION: Lower lung volumes and higher BMI are likely related to lower levels of nocturnal oxygen saturation. Lowest oxygen saturation and average oxygen saturation levels are significantly lower in obese men than in obese women.
CLINICAL IMPLICATIONS: Obese men and obese women have a reduction in nocturnal oxygen saturation. Lowest oxygen saturation and average oxygen saturation levels are significantly lower in obese men than in obese women.
DISCLOSURE: Gautham Ravipati, None.