PURPOSE: The measurement of maximal respiratory pressures (PImax & PEmax) is now possible for most pulmonary function laboratories. These are direct tests that are simple to perform to assess the aggregate force or pressure that respiratory muscles can generate against an occlusion at the mouth. PImax is an index of the strength of the diaphragm, while PEmax measures the strength of abdominal and intercostal muscles. These measurements have a role in the diagnosis and quantification of respiratory muscle weakness in patients who have dyspnoea and respiratory failure and neuromuscular disease. Studies have obtained prediction equations for the Caucasian population and, only a few studies address all age groups. Since no study has attempted to determine the prediction equations for the Indian population; this study was designed.
METHODS: The study was performed in a tertiary care teaching hospital in India. Four hundred healthy volunteers (242 males and 158 females) were recruited from among the patient relatives, hospital staff and students and the residents of Vellore town in the 15 –78 age group. Subjects with more than 10 pack year smoking history and those with abnormal spirometry were excluded. The age, weight, height and BMI were incorporated in a step wise multiple regression analysis to determine prediction equations for both male and female subjects.
RESULTS: The mean PImax; was 10.59 kPa for men and 7.65 kPa in women and the mean PEmax was 12.94 kPa in men and 8.86 kPa in women, both values being higher in men. For PImax significant correlation was found with age, weight, FEV1, PEF & FVC in both men and women. For PEmax; significant correlation was found with age, weight, FEV1, PEF and FVC in men and in women, in addition; there was significant correlation with height.
CONCLUSION: We have derived the first set of prediction equations for maximal respiratory pressures (PImax and PEmax) for the Indian population.
CLINICAL IMPLICATIONS: This could be used in clinical and research settings.
DISCLOSURE: Devasahayam Christopher, None.