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Abstract: Poster Presentations |

LUNG FUNCTION IMPAIRMENT AND REHABILITATION STRATEGY FOR PATIENTS WITH MUSCULAR DYSTROPHY FREE TO VIEW

Zhiping Li, RRT*; Yun Zhong, MD; Yubiao Guo, MD, PhD; Jianqiang Huang, MD, PhD; Lihong Peng, MD; Xiaoli Yao, MD, PhD; Cheng Zhang, MD, PhD
Author and Funding Information

First Affiliated Hospital Sun Yat Set Univ Pulm & CCM, Guangzhou, Peoples Rep of China



Chest. 2006;130(4_MeetingAbstracts):246S. doi:10.1378/chest.130.4_MeetingAbstracts.246S-a
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Abstract

PURPOSE: To compare the characteristics of lung function impairment in three groups of patients with Becker’s Muscular Dystrophy(BMD) and Duchenne’s Muscular Dystrophy(DMD) and try to approach the rehabilitation strategy.

METHODS: Lung function were measured and compared among three groups of Muscular Dystrophy patients. Patients in Group A suffered from BMD. Patients in Group B were those with DMD and insisted on long-term rehabilitation exercise, while patients in Group C were those with DMD and nearly never had rehabilitation exercise.

RESULTS: Lung function parameters of Group A were in normal range as the following: FVC% was 82±15%, FEV1% was 91±18%•MVV% was 98±32%. Lung function was impaired in both Group B and Group C. In Group B, FVC% was 64±11%•FEV1% was 74±13%•MVV% was 82±19%. In Group C, FVC% was 37±12%•FEV1% was 43±15%•MVV% was 52±19%. There were statistically significant differences among the three groups in FVC%, FEV1% and MVV% (P<0.05), while no significant differences in FEV1/FVC (P>0.05).

CONCLUSION: Although the main lung function parameters of BMD patients were in normal range, the abnormally increased FEV1/FVC in both BMD and DMD patients demonstrated that restrictive ventilation disorder was common characteristic in patients with muscular dystrophy.

CLINICAL IMPLICATIONS: Rehabilitation exercise might be helpful for slowing the lung function deterioration, while rehabilitation exercise specifically aiming at respiratory muscles might be more helpful in that it could improve the restrictive ventilation disorder in muscular dystrophy patients.

DISCLOSURE: Zhiping Li, None.

Wednesday, October 25, 2006

12:30 PM - 2:00 PM


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