PURPOSE: Quality of life in patients after successful therapy (Rx) for Wilms tumor (WT) could be influenced by possibly disturbed lung function. Studies on pulmonary function (PFT) long-term after successful Rx for WT are rare1,2.
METHODS: Eight patients in remission of 15.4±4.1; median 16.3 yrs were tested at the age of 19.4±3.7; median 20,5 yrs. Only chemotherapy with no lung irradiation was performed in our group. Static lung volumes and central/peripheral airway patency were measured.
RESULTS: RESULTS (mean value of % predicted±SD):.
CONCLUSION: Normal mean values of indices of the lung size and peripheral airway patency were found long-term after successful Rx for WT. Mild signs of lung hyperinflation were detected. Index of central airway patency (sGaw) slightly increased indicating quite normal central airway patency. References:1Attard-Montalto SP et al: Br J Radiol 1992; 65: 1114-1118; 2Leupold W et al: Pneumologie 1990; 44: 1213-1216 Supported by grant NR 8796-3 of the Int. Grant Agency of the Czech Ministry of Health.
CLINICAL IMPLICATIONS: Good clinical condition and normal lung size in our cohort might correlate with monotherapy (i.e., no whole lung irradiation) used.
DISCLOSURE: Jan Sulc, None.