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Abstract: Poster Presentations |

LUNG FUNCTION IN PATIENTS IN LONG-TERM REMISSION OF WILMS TUMOR: PILOT STUDY FREE TO VIEW

Jan Sulc, MD, FCCP*; Jitka Radvanska, MD; Jiri Radvansky, MD; Krystof Slaby, MD; Marcela Safarova, MSc
Author and Funding Information

Univ. Hosp. Motol, Prague, Czech Republic



Chest. 2006;130(4_MeetingAbstracts):241S. doi:10.1378/chest.130.4_MeetingAbstracts.241S-a
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Abstract

PURPOSE: Quality of life in patients after successful therapy (Rx) for Wilms tumor (WT) could be influenced by possibly disturbed lung function. Studies on pulmonary function (PFT) long-term after successful Rx for WT are rare1,2.

METHODS: Eight patients in remission of 15.4±4.1; median 16.3 yrs were tested at the age of 19.4±3.7; median 20,5 yrs. Only chemotherapy with no lung irradiation was performed in our group. Static lung volumes and central/peripheral airway patency were measured.

RESULTS: RESULTS (mean value of % predicted±SD):.

CONCLUSION: Normal mean values of indices of the lung size and peripheral airway patency were found long-term after successful Rx for WT. Mild signs of lung hyperinflation were detected. Index of central airway patency (sGaw) slightly increased indicating quite normal central airway patency. References:1Attard-Montalto SP et al: Br J Radiol 1992; 65: 1114-1118; 2Leupold W et al: Pneumologie 1990; 44: 1213-1216 Supported by grant NR 8796-3 of the Int. Grant Agency of the Czech Ministry of Health.

CLINICAL IMPLICATIONS: Good clinical condition and normal lung size in our cohort might correlate with monotherapy (i.e., no whole lung irradiation) used.

DISCLOSURE: Jan Sulc, None.

Wednesday, October 25, 2006

12:30 PM - 2:00 PM


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