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Abstract: Poster Presentations |

CARDIAC FUNCTION IN PATIENTS WITH BRONCHIECTASIS FREE TO VIEW

Abdulaziz H. Alzeer, FRCP*
Author and Funding Information

King Khalid University Hospital, Riyadh, Saudi Arabia



Chest. 2006;130(4_MeetingAbstracts):226S-d-227S. doi:10.1378/chest.130.4_MeetingAbstracts.226S-d
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Abstract

PURPOSE: To evaluate the cardiac function in patients with cystic (non-perfused) and cylindrical (perfused) bronchiectasis with emphasis on pulmonary artery pressure and to correlate the findings with the pulmonary function tests and C-T scan score.

METHODS: Ninety four patients, 65 (69%) females with mean age (± SD) 53.4 ± 17.7 years with the diagnosis of bronchiectasis proven by chest CT scan were recruited from out-patient clinic between July 2004 to June 2005. Echocardiography and pulmonary function tests were performed to all patients.

RESULTS: Left ventricular dysfunction (LVEF < 45%) was observed in 4% and right ventricular dysfuncion was observed in 10%. The prevalence of pulmonary hypertension (PAP > 35 mm Hg) was 43.9% in cystic vs 19.2% in cylindrical bronchiectasis(p-value <0.04). The right ventricular dimension was significantly higher in cystic disease (p-value 0.02), where as there was no statistical difference between left ventricular and right ventricular stroke volume among the two groups. Pulmonary pressure was negatively correlated with PO2, DLCO%, and FEV1 (p-value <0.0001) and positively was correlated with PCO2 (p-value <0.001), R2 = 0.21. Pulmonary hypertension was correlated with C-T scan score (p-value < 0.03), R2 = 0.05.

CONCLUSION: Left ventricular function was preserved in patients with bronchiectasis. Pulmonary hypertension was more prevalent in cystic disease and was correlated with deteriorated pulmonary function and high C-T scan sore.

CLINICAL IMPLICATIONS: Close follow up of patients with cystic bronchiectasis is warranted as early surgical intervention may avert further haemodynamic deterioration.

DISCLOSURE: Abdulaziz Alzeer, None.

Wednesday, October 25, 2006

12:30 PM - 2:00 PM


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