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Abstract: Poster Presentations |

INCIDENCE OF IN-HOSPITAL MORTALITY OR NONFATAL MYOCARDIAL INFARCTION OR NONFATAL STROKE IN 216 DIABETICS AND IN 552 NONDIABETICS UNDERGOING PERCUTANEOUS CORONARY INTERVENTION WITH STENTING FREE TO VIEW

Sarah M. Gamble, DO*; Leonardo N. Saulle, MD; Wilbert S. Aronow, MD; Rose M. Alappat, DO; Kumar Kalapatapu, MD; Anthony L. Pucillo, MD; Craig E. Monsen, MD; Melvin B. Weiss, MD
Author and Funding Information

New York Medical College, Valhalla, NY



Chest. 2006;130(4_MeetingAbstracts):199S. doi:10.1378/chest.130.4_MeetingAbstracts.199S-a
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Abstract

PURPOSE: To investigate the incidence of in-hospital mortality or nonfatal myocardial infarction (MI) or nonfatal stroke in diabetics versus nondiabetics undergoing percutaneous coronary intervention (PCI) with stenting.

METHODS: During a 6 month period, 216 diabetics and 552 nondiabetics (68% men and 32% women, mean age 66 years) underwent PCI with stenting. Symptomatic chest pain was present in 95% of diabetics and in 95% of nondiabetics. Unstable symptoms were present in 67% of diabetics and in 68% of nondiabetics, p not significant (NS). The prevalence of significant 3-or 4-vessel coronary artery disease (CAD) was 34% in diabetics versus 23% in nondiabetics, p < 0.001. The prevalence of significant 2-vessel CAD was 43% in diabetics versus 44% in nondiabetics, p NS. The prevalence of significant 1-vessel CAD was 23% in diabetics versus 33% in nondiabetics, p < 0.005. Aspirin was used to treat 99% of diabetics and nondiabetics. Clopidogrel was used to treat 98% of diabetics and nondiabetics. Beta blockers were used to treat 85% of diabetics and nondiabetics. Lipid-lowering drugs were used to treat 96% of diabetics and 95% of nondiabetics, p NS.

RESULTS: In-hospital mortality occurred in 2 of 216 diabetics (0.9%) versus 2 of 552 nondiabetics (0.4%), p NS. In-hospital mortality or nonfatal MI occurred in 3 of 216 diabetics (1.4%) versus 5 of 552 nondiabetics (0.9%), p NS. In-hospital mortality or nonfatal MI or nonfatal stroke occurred in 3 of 216 diabetics (1.4%) versus 6 of 552 nondiabetics (1.1%), p NS.

CONCLUSION: The incidence of in-hospital mortality or nonfatal MI or nonfatal stroke is low and not significantly different in diabetics versus nondiabetics with unstable or stable symptoms treated with aspirin, clopidogrel, beta blockers, and lipid-lowering drugs.

CLINICAL IMPLICATIONS: Diabetics as well as nondiabetics with unstable or stable symptoms undergoing PCI have a low incidence of in-hospital mortality or nonfatal MI or nonfatal stroke if they are treated with stenting, aspirin, clopidogrel, beta blockers, and lipid-lowering drugs.

DISCLOSURE: Sarah Gamble, None.

Wednesday, October 25, 2006

12:30 PM - 2:00 PM


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