PURPOSE: Background: Correlation between right and left ventricular ejection fraction has not been studied in patients with or without cardiomyopathy. The goal of this study was to compare right and left ventricular ejection fractions in the patients with or without cardiomyopathy using blood pooled scintigraphy.
METHODS: Methods: We studied a series of 152 patients, who underwent left ventricular ejection fraction (LVEF) calculation for a clinical indication and underwent simultaneous measurement of the right ventricular ejection fraction (RVEF). The correlation between right and left ventricular ejection fraction in patients with or without cardiomyopathy were measured using regression analysis.
RESULTS: Results: Although, right and left ventricular ejection fractions were significantly correlated in the entire cohort in a S curve mathematical function, the correlation was very poor (r= 0.32, p< 0.0001). However, the correlation was linear and stronger in patients with Cardiomyopathy (defined as LVEF and RVEF <50%, r=0.41, p<0.0001) and was completely absent in patients without cardiomyopathy (LVEF and RVEF > 50%, r=.001, p=0.86). Strongest RVEF and LVEF correlation occurred in patients with LVEF and RVEF < 30%, (r=0.75, p = 0.03).
CONCLUSION: Conclusion: Only patients with cardiomyopathy have significant correlation between LVEF and RVEF.
CLINICAL IMPLICATIONS: The cause of this strong discrepancy between patients with or without cardiomyopathy is not known and warrants future investigation.
DISCLOSURE: Mohammad-Reza Movahed, None.