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Abstract: Poster Presentations |

CHRONIC OBSTRUCTIVE PULMONARY DISEASE DOES NOT EFFECT LEFT OR RIGHT VENTRICULAR EJECTION FRACTIONS FREE TO VIEW

Mohammad-Reza Movahed, MD,PhD*; Norah Milne, MD
Author and Funding Information

Department of Medicine, University of California, Irvine, Orange, CA



Chest. 2006;130(4_MeetingAbstracts):170S. doi:10.1378/chest.130.4_MeetingAbstracts.170S-b
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Abstract

PURPOSE: Background: Whether there is increased prevalence of right and left ventricular dysfunction in smoking patients is not known and in patients with chronic obstructive lung disease (COPD) has been controversial. The goal of this study was to evaluate the prevalence of decreased left and right ventricular ejection fraction (RVEF and LVEF) in patients with smoking or diagnosis of COPD in comparison to a control group.

METHODS: Methods: A series of 157 patients, who underwent LVEF assessment using blood pooled scintigraphy for clinical indications, underwent simultaneous measurement of RVEF. Patients with a history of COPD were compared to a control group.

RESULTS: Results: LVEF was measured in 155 and RVEF was measured in 152 patients. Mean LVEF in patient with COPD (13 patients) was 46.5 ± 16.8 SD vs. 53.2 ± 16.4 SD in the control group ( 142 patient) p=0.16. Mean RVEF in patient with COPD (12 patients) was 46.8± 13.9 SD vs. 50.8 ± 12.7 SD in the control group ( 140 patients) p=0.29. Subgroups analysis of mild, moderate or severe LVEF and RVEF dysfunction revealed no statistical differences between the patients with or without smoking or diagnosis of COPD.

CONCLUSION: Conclusion: Patients with smoking or a diagnosis of COPD have similar RVEF or LVEF in comparison to a control group.

CLINICAL IMPLICATIONS: Our Study suggests that stable COPD or smoking are not independent risk for decreased cardiac performance.

DISCLOSURE: Mohammad-Reza Movahed, None.

Wednesday, October 25, 2006

12:30 PM - 2:00 PM


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