PURPOSE: Health Related Quality of Life in sarcoidosis patients (pts) was measured during one year follow- up period using Sarcoidosis Health Questionnaire as the disease specific HRQOL instrument.
METHODS: Out of 200 biopsy positive sarcoidosis patients (pts) the two different groups were chosen depending on the clinical course of sarcoidosis. Group I pts with acute sarcoidosis 108 pts (54%) and Group II pts with chronic sarcoidosis 92 (46%). All patients completed SHQ at the beginning of the study and again one year later. The mean SHQ scores were calculated using PC Excel Calculator, originally designed for SHQ with author's permission. The mean SHQ scores at the beginning of the study and one year later were compared using paired samples statistics. (Correlations and T test). A probability value of p< 0.05 was considered to be statistically significant.
RESULTS: In Group I- acute sarcoidosis -after one year statistically significant improvement was found within the domains of the : Daily score Physical score and Total score. (sig <0,05). In Group II- chronic sarcoidosis- the statistically significant improvement within the domains of Physical score and Emotional score (sign < 0.05) was noticed after one year follow up period.
CONCLUSION: HRQOL within one year follow -up period measured using SHQ showed the correlation with the clinical course of the disease. The expected improvement of the HRQOL correlates with the expected clinical improvement of patients with acute disease vs. patients with chronic disease.
CLINICAL IMPLICATIONS: The use of SHQ is firmly suggested as an instrument of the HRQOL in sarcoidosis.
DISCLOSURE: Violeta Vucinic, None.