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Abstract: Slide Presentations |

COMBINED ENDOSCOPIC TRANSBRONCHIAL AND TRANSESOPHAGEAL ULTRASOUND-GUIDED BIOPSY OF CENTRALLY LOCATED LUNG TUMOURS FOLLOWING A NONDIAGNOSTIC BRONCHOSCOPY FREE TO VIEW

Mark Krasnik, MD*; Peter Vilmann, MD; Birgit G. Skov, MD; Armin Ernst, MD; Ralf Eberhardt, MD; Felix Herth, MD
Author and Funding Information

Gentofte University Hospital, Hellerup, Denmark



Chest. 2006;130(4_MeetingAbstracts):116S. doi:10.1378/chest.130.4_MeetingAbstracts.116S-a
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Abstract

PURPOSE: The aim of the present study was to test the use of EBUS-TBNA and EUS-FNA in patients with an undiagnosed solid lesion of unknown origin in the lung outlined by CT.

METHODS: The combination of EBUS-TBNA and EUS-FNA was prospective performed in 52 patients. 5 patients with a tumour in the mediastinum and 47 with undiagnosed tumour in the lungs. Bronchoscopy and TBNA have been performed in all patients without obtaining a diagnosis.

RESULTS: A total of 5 tumours and 103 lymph nodes were biosied. EBUS TBNA was positive for cancer in 34 lymph nodes and 5 tumours and by EUS poitive for cancer in 5 tumours and 37 patients. In 3 lesions the specimen was without conclusive material.In 31 patients a malignant diagnose was obtained. In 3 patients a specific non malignant diagnose was obtained (sarcoidosis, thymoma and fungal infection). In 20 patients normal lymph cells were obtained. All the diagnosis was confirmed either by mediastinoscopy or Thoracotomy/scopy. The diagnostic yield was 97% (105/108)The diagnose was obtained by EBUS-TBNA in 29 patients and by EUS-FNA in 28 patients. In 3 patients the diagnose was obtained only by EBUS-TBNA and only by EUS in 28 patients In 1 patient both EUS and EBUS were false negative- the malignant diagnose was obtained by puncture of N1 lymph nodes.

CONCLUSION: EBUS-TBNA is an effective and non invasive method to obtain a diagnose in patients with lesions of unknown origin in the mediastinum and hillar regions.

CLINICAL IMPLICATIONS: With the combined use of EBUS- TBNA and EUS-FNA is not only diagnostic but staging is also obtained with the diagnostic procedure.

DISCLOSURE: Mark Krasnik, None.

Tuesday, October 24, 2006

10:30 AM - 12:00 PM


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