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A 36-Year-Old Man With Seizures and Multiple Cystic Pulmonary NodulesSeizures and Multiple Cystic Pulmonary Nodules

Megan L. Krause, MD; Richard K. Patch, MD; Sean M. Caples, DO
Author and Funding Information

From the Internal Medicine Residency Program (Dr Krause); and the Division of Pulmonary and Critical Care Medicine (Drs Patch and Caples), Department of Medicine, Mayo Clinic, Rochester, MN.

Correspondence to: Megan L. Krause, MD, Department of Medicine, Mayo Clinic, 200 First St SW, Rochester, MN 55905; e-mail: Krause.Megan@mayo.edu


Funding/Support: Dr Caples is supported by the National Institutes of Health [Grant HL99534Z].

Reproduction of this article is prohibited without written permission from the American College of Chest Physicians. See online for more details.


Chest. 2012;142(1):256-259. doi:10.1378/chest.11-2223
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Funding/Support: Dr Caples is supported by the National Institutes of Health [Grant HL99534Z].

Reproduction of this article is prohibited without written permission from the American College of Chest Physicians. See online for more details.

WillmanCLBusqueLGriffithBB. Langerhans’-cell histiocytosis (histiocytosis X)—a clonal proliferative disease. N Engl J Med. 1994;331(3):154-160.MalpasJSNortonAJ. Langerhans cell histiocytosis in the adult. Med Pediatr Oncol. 1996;27(6):540-546.Report of the Histiocyte Society workshop on “Central nervous system (CNS) disease in Langerhans cell histiocytosis (LCH). Med Pediatr Oncol. 1997;29(2):73-78.MalpasJS. Langerhans cell histiocytosis in adults. Hematol Oncol Clin North Am. 1998;12(2):259-268.EgelerRMFavaraBEvan MeursMLamanJDClaassenE. Differential in situ cytokine profiles of Langerhans-like cells and T cells in Langerhans cell histiocytosis: abundant expression of cytokines relevant to disease and treatment. Blood. 1999;94(12):4195-4201.KaltsasGAPowlesTBEvansonJ. Hypothalamo-pituitary abnormalities in adult patients with langerhans cell histiocytosis: clinical, endocrinological, and radiological features and response to treatment. J Clin Endocrinol Metab. 2000;85(4):1370-1376.VassalloRRyuJHColbyTVHartmanTLimperAH. Pulmonary Langerhans’-cell histiocytosis. N Engl J Med. 2000;342(26):1969-1978.JainRS. Langerhans cell histiocytosis presenting as adult onset epilepsy. Int J Clin Pract. 2003;57(8):739-741.GötzGFichterJ. Langerhans’-cell histiocytosis in 58 adults. Eur J Med Res. 2004;9(11):510-514.GroisNFahrnerBArceciRJHistiocyte Society CNS LCH Study Group. Central nervous system disease in Langerhans cell histiocytosis. J Pediatr. 2010;156(6):873-881.

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