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Abstract: Poster Presentations |

TREATMENT OUTCOME OF TUBERCULOSIS UNDER DIRECTLY OBSERVED TREATMENT SHORT COURSE ( DOTS ) IN PATIENTS PRESENTING AT CHEST & TB HOSPITAL, AMRITSAR FREE TO VIEW

Vishal Verma, MBBS; Jorawar Singh, MBBS; Nirmal Chand, MS*; J. S. Khalsa, MBBS
Author and Funding Information

Dept. of Tuberculosis & Respiratory Diseases, Amritsar, India


Chest


Chest. 2005;128(4_MeetingAbstracts):403S-b-404S. doi:10.1378/chest.128.4.2824
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Published online

Abstract

PURPOSE:  The present study was undertaken to determine the treatment outcome of DOTS as prescribed under RNTCP. Side effects and radiological improvement was also noted.

METHODS:  A total of 150 cases of tuberculosis on the basis of history, sputum & radiological examination were selected. They were divided into three categories under RNTCP. All the patients were administered standard regimens of antitubercular drugs as prescribed under DOTS. Sputum of all patients was examined before the start of treatment and then at the end of intensive phase, 4or5or6 months and then at the end of treatment. X-ray was taken before and at the end of treatment. Treatment outcome was determined.

RESULTS:  150 patients comprised of 91 males and 59 females. Cough was the major complaint in 70% . Sputum conversion rate was 81% & 85.71% for category I & II. Cure rate was 91% & 71.40% for category I & II. Treatment completion rate was 100% for category III. Overall default rate was 5.33%. Failure rate was 0.67%. Radiological improvement was seen in 73.33%. 60.67% gained weight in the range of 6-10 Kg. Fatigue was major side effect under DOTS in 24% cases.

CONCLUSION:  DOTS is an effective and economical treatment with successful treatment outcome, sputum conversion and minimal side effects for tuberculosis.

CLINICAL IMPLICATIONS:  DOTS in an effective therapy in developing countries like india whose almost 40% of the population in infected with tuberculosis.

DISCLOSURE:  Nirmal Chand, None.

12:30 PM - 2:00 PM


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