Performance on cardiopulmonary exercise test (CPET) is influenced by genetic, racial and environmental factors. Normal reference values derived from Caucasian populations are not deemed appropriate if CPET is done among non-Caucasian subjects. It is important to establish a set of reference values for the Filipino population. The objectives of this study were to (1) establish the Maximum Working Capacity, Peak oxygen intake (VO2), Peak carbon dioxide output (VCO2), Tidal Volume (TV) for normal Filipinos during exercise, (2) determine the median perceived rate of exertion using the Borg Scale, and (3) derive prediction equation models for Maximum Working Capacity, Peak VO2 , Peak VCO2 and maximum attained TV.
The maximal cardiopulmonary responses were analyzed for one hundred eighteen healthy sedentary adult Filipino subjects who underwent CPET using a symptom limited incremental progressive cycle ergometer driven protocol. A Vista Mini-CPX Model 17670 was used. Models for predicting VO2 max, VCO2 peak, VT peak, and Work max were derived with height, weight, age and sex being screened for significance as predictors of the said parameters. Linear and non-linear regression was done.
The maximum working capacity for males was 154.21±26.6 watts and 93.02±15.57 watts for females while the peak VO2 for males was 4.90±3.11 and 4.56±2.41 liters/minute for females. The predictive formulae derived from our study for maximum work capacity, peak VO2, VCO2 and tidal volume had acceptable correlation coefficients and performed as well as other published predictive equations based on Caucasian and Asian populations.
Cardiopulmonary exercise testing was performed on a community based, healthy, sedentary Filipino population using a standard maximal incremental cycle ergometry protocol. Predictive equation models were derived for Maximum Working Capacity(r2 =0.728), peak VO2 (r2=0.123), peak VCO2(r2=0.648) and TV (r2 =0.579). The derived predictive formulae performed as well as other published predictive equations.
Differences in response to cardiopulmonary exercise testing among racial populations do exist and normal reference values for different populations should be obtained and utilized for proper interpretation of these tests.
Lenora Fernandez, Grant monies (from industry related sources) Boehringer-Ingelheim (Philippines) Research Medical Foundation, Incorporated.