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Abstract: Poster Presentations |

PATTERN AND DETERMINANTS OF SURVIVAL AMONG LUNG CANCER PATIENTS IN WESTERN PART OF INDIA FREE TO VIEW

Ramakant Dixit, MD; Sidharth Sharma, MBBS*
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J.L.N. Medical College, Ajmer, India


Chest


Chest. 2005;128(4_MeetingAbstracts):336S. doi:10.1378/chest.128.4_MeetingAbstracts.336S-a
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Abstract

PURPOSE:  As a global problem, India is also witnessing the increasing trends of lung cancer in both sexes. Despite many sporadic reports on the clinical, radiological and pathological features of lung cancer from different part of country, Indian literature is scanty on the survival aspect of lung cancer patients. The present study is first one on pattern and determinants of survival among various histological types of lung cancer patients from Western India.

METHODS:  cases of histologically proven lung cancer patients were evaluated in the light of clinical, radiological & pathological features. According to the histological diagnosis stage of the disease and performance status, patients received various treatment modalities. Those coming in follow up constituted the study population.

RESULTS:  Lifespan could be assessed in 122 patients (110 males and 12 females). 75.3% patients died within 6 moths of diagnosis and only 6.5% survived more than a year. About 50% patients having performance India 3 or 4 died within 3 months of their diagnosis. 42.8% cases of squamous cell carcinoma, 45.4% of adenocarcinoma and 50% of small cell carcinoma survived no longer than 6 months. Average life span in SCLC was 4.9% months and 4.1 months in NSCLC 55% of SCLC patients with ED died within 3 months of diagnosis while similar proportion of stage III b and 83% of stage IV NSCLC patients died within 6 months In both SCLC and NSCLC, Survival was better in those with performance index zero or one and those receiving the chemotherapy. Generalized debility due to relapse, progression of disease or treatment related advance effects was the commonest terminal event (67.2%) followed by pulmonary embolism (31.1%), renal failure (14.7%) & others.

CONCLUSION:  In our study the survival of patients with advanced disease was poor and survival decreased further with poor performance status.

CLINICAL IMPLICATIONS:  : Survival in lung cancer patients is poor in this vary part of India and is significantly influenced by stage of the disease, histological type, performance index and treatment modalities etc.

DISCLOSURE:  Dr.Sidharth Sharma, None.

Wednesday, November 2, 2005

12:30 PM - 2:00 PM


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