Abstract: Poster Presentations |


Mayank Vats, MD*; Rakesh C. Gupta, MD; Deepa V. Khandelwal, MBBS; Neeraj Gupta, MD; Maheep Saluja, MD; Mukesh Tailor, MBBS
Author and Funding Information

J.L.N. Medical College, Ajmer, Rajasthan, India


Chest. 2005;128(4_MeetingAbstracts):328S-c-329S. doi:10.1378/chest.128.4_MeetingAbstracts.328S-c
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PURPOSE:  Most common indication of flexible bronchoscopy (FOB) in our setting is bronchogenic carcinoma, usually associated with Chronic-Obstructive-Pulmonary-Disease, concomitant infection, and hence hypoxia. The aim of study was to establish the value of O2 -supplementation during FOB to avoid catastrophic consequences of hypoxemia.

METHODS:  Forty patients of C.O.P.D. and 10 controls were studied for oxygen saturation (SpO2) by pulse-oximetry during FOB and classified into: -Group-1 (n=10):Age-&-sex matched healthy controls. Group-2A (n=10):FOB without O2-supplementationGroup-2B (n=15):FOB with O2-supplementation {nasal-catheter (rate-3 liters/min)}.Group-2B (n=15):FOB with O2-supplementation {pharyngeal-catheter (rate-3 liters/min)}.

RESULTS:  In control-group mean % fall from baseline-values in PFT after premedication and local anaesthesia (L.A.) and in study-group after premedication it was insignificant (p>0.05). In study-group mean % fall from baseline after L.A. was 16.4±4% in FVC, 11.2±2.6% in FEV1 and 12.1±5.5% in PEFR in group-2A, 14.8±3.5% in FVC, 15.5±3.9% in FEV1 and 16±6% in PEFR in group-2B and 15.9±5.4% in FVC, 16.3±5.5% in FEV1 and 13±1.1% in PEFR in group-2C patients (p<0.01, Highly Significant). In control-group mean-SaO2 at baseline was 97.7±2%.( Mean decline was-1.1%) (p>0.05). In 2A-group mean-fall in SpO2 after L.A. was insignificant but highly significant fall of 7.9% in the mean SpO2 during FOB (p<0.001) and significant rise of 3.5% just after BronchoAlveolar Lavage( BAL) (p<0.001) were observed. In group-2B patients significant rise in SpO2 was observed during FOB (p<0.01) and after BAL (p<0.001) and mean SpO2 were higher than the baseline. In group-2C, significant rise in mean SpO2 were observed during, after BAL and 20-min after FOB. Transient hypoxemia (SpO2 <85%) was observed in group-2A-40% cases, 2B-6.6% and 2C-1.2% cases. Minimum SpO2 observed during FOB were group-2A-87±4%, group-2B-92±3% and group-2C- 94±4%.

CONCLUSION:  During FOB, SaO2 levels were significantly better in patients with O2 –supplementation and were almost similar with nasal and pharyngeal-catheters.

CLINICAL IMPLICATIONS:  The need for pulse-oximetry and significance of O2-supplementation in patients with hypoxia is emphasized.

DISCLOSURE:  Mayank Vats, None.

Wednesday, November 2, 2005

12:30 PM - 2:00 PM




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