The aim of the present study was to test the use of EBUS-TBNA in the evaluation of mediastinal and hillar lesions in patients with an undiagnosed solid lesion of unknown origin in the mediastinum and hillar regions or enlarged lymph nodes in the mediastinum outlined by CT.
EBUS TBNA was prospective performed in 110 patients. 7 patients with a tumour in the mediastinum and 103 patients with enlarged lymph nodes in the mediastinum or the hillar regions. Bronchoscopy and TBNA have been performed in all patients without obtaining a diagnosis.
A total of 7 tumours and 230 lymph nodes were biosied. EBUS TBNA was positive for cancer in 144 lymph nodes and 6 tumours. In 7 lesions the specimen was without conclusive material.In 85 patients a malignant diagnose was obtained. In 18 patients a specific non malignant diagnose was obtained (sarcoidosis, thymus, ectopic thyroid, granolomateous infection and fungal infection).. All the diagnosis was confirmed either by EUS, mediastinoscopy or Thoracotomy/scopy. The diagnostic yield was 98% In 8 patients the malignant diagnose was obtained by puncture of N1 lymph nodes.
EBUS TBNA is an effective and non invasive method to obtain a diagnose in patients with lesions of unknown origin in the mediastinum and hillar regions.
Mark Krasnik, None.