0
Abstract: Poster Presentations |

ADJUVANT CHEMOTHERAPY AFTER SURGICAL RESECTION FOR SMALL-CELL CARCINOMA OF LUNG FREE TO VIEW

Euntaik Jeong, MD*; Hakryul Kim, MD
Author and Funding Information

Wonkwang Univ. Hospital, Iksan Jeonbuk, South Korea


Chest


Chest. 2005;128(4_MeetingAbstracts):312S. doi:10.1378/chest.128.4_MeetingAbstracts.312S-a
Text Size: A A A
Published online

Abstract

PURPOSE:  Small-cell carcinoma of lung has a tendency of rapid growth and early wide metastasis. In spite of high response rate of combination chemotherapy alone or with radiotherapy, overall long term survival rate is very disappointed. According to autopsy findings, the common cause of failure is local recurrence in primary cancer site. So, surgical resection with combined chemotherapy has been recently attempted for very early stage of small-cell carcinoma of lung.

METHODS:  We treated 10 patients (TNM I: 5 cases, II: 5 cases) undergoing surgical resection for small-cell carcinoma of lung with adjuvant chemotherapy in an attempt to prolong survival. Of these, 9 patients received chemotherapy, and retrospective study was undertaken for survival (Kaplan-Meier analysis).

RESULTS:  Median survival time was 26 months, 2-, 5-year survival rate was 68.6%, 46.7%. If 1 patient without chemotherapy was excluded, 2-, 5-year survival rate was 76.2%, 50.8%. No survival difference was seen between patients with TNM I, II stages.

CONCLUSION:  Adjuvant chemotherapy after surgical resection results in prolonged survival for patients with TNM stage I, II small-cell carcinoma of lung.

CLINICAL IMPLICATIONS:  We can apply this adjuvant chemotherapy after surgical resection for the improvemnet of survival of patients with early stage small-cell carcinoma of lung.

DISCLOSURE:  Euntaik Jeong, None.

Wednesday, November 2, 2005

12:30 PM - 2:00 PM


Figures

Tables

References

NOTE:
Citing articles are presented as examples only. In non-demo SCM6 implementation, integration with CrossRef’s "Cited By" API will populate this tab (http://www.crossref.org/citedby.html).

Some tools below are only available to our subscribers or users with an online account.

Related Content

Customize your page view by dragging & repositioning the boxes below.

  • CHEST Journal
    Print ISSN: 0012-3692
    Online ISSN: 1931-3543