0
Abstract: Poster Presentations |

DOES VARIATION ON SURGICAL TECHNIQUES ALTER OUTCOME OF LUNG BIOPSY FOR INTERSTITIAL LUNG DISEASE? FREE TO VIEW

Bhanumathi Lakshminarayanan, MD*; Antonio E. Martin-Ucar, MD; Michael F. Maguire, MD; Lynda Beggs; David Beggs, MD; John P. Duffy, MD; Ellis Morgan, MD
Author and Funding Information

Thoracic Surgery, Nottingham City Hospital, Nottingham, United Kingdom


Chest


Chest. 2005;128(4_MeetingAbstracts):309S. doi:10.1378/chest.128.4_MeetingAbstracts.309S
Text Size: A A A
Published online

Abstract

PURPOSE:  The reported accuracy of surgical biopsy for interstitial lung disease (ILD) is highly variable. We have audited our results to determine whether operative techniques do alter outcomes.

METHODS:  123 patients [68 men and 55 women with a median age of 57 (range from 18 to 84) years] underwent lung biopsy for diffuse interstitial lung disease in our unit from 1992 to 2004. Video assisted thoracoscopy (VATS) was used on 66 cases (54%) and the rest underwent traditional open biopsy. Outcomes of the study were: rate of definitive specific diagnosis, change of diagnosis and change of therapy, complications, and to assess the weight of surgical variables (surgical procedure, side, number and size of samples) as predictors of outcomes.

RESULTS:  There was one postoperative death (0.8%) and 13 patients (10%) had any complication. A definitive specific diagnosis was obtained in 91 cases (74%). A different diagnosis from presumed pre-operative one was encountered on 59 (48%) cases, and a definite change of therapy was confirmed on 27 (22%) of cases. The type of procedure (either VATS or open), or number and size of specimens did not significantly affect the chance of a definitive diagnosis, complications, change of diagnosis, or change in therapy. (Table 1, p= non significant in all cases).

CONCLUSION:  Lung biopsy can be done safely with high rates of specific diagnosis and low incidence of complications. We have not proven that surgical variables alter the outcomes in terms of definitive or change of diagnosis, complications or change of therapy.

CLINICAL IMPLICATIONS:  Different approaches and techniques do not contribute to increase usefulness of surgical biopsy for ILD. Specific diagnosisChange of diagnosisChange of therapyTechniqueVATS (n=66)50 (76%)28 (42%)14 (21%)Open (n=57)41 (72%)31 (54%)13 (23%)SideRight (n= 64)47 (73%)33 (51%)13 (20%)Left (n= 59)44 (75%)26 (44%)14 (24%)Number1 sample (n=105)76 (72%)51 (49%)22 (21%)1 sample (n=18)15 (83%)8 (44%)5 (28%)Size<4cm (n= 69)50 (72%)30 (43%)12 (17%)>4cm (n=54)39 (72%)27 (50%)15 (28%)

DISCLOSURE:  Bhanumathi Lakshminarayanan, None.

Wednesday, November 2, 2005

12:30 PM - 2:00 PM


Figures

Tables

References

NOTE:
Citing articles are presented as examples only. In non-demo SCM6 implementation, integration with CrossRef’s "Cited By" API will populate this tab (http://www.crossref.org/citedby.html).

Some tools below are only available to our subscribers or users with an online account.

Related Content

Customize your page view by dragging & repositioning the boxes below.

  • CHEST Journal
    Print ISSN: 0012-3692
    Online ISSN: 1931-3543