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Abstract: Poster Presentations |

THE EFFECTIVENESS OF THE MISTY-OX HIGH FRACTION OF INSPIRED OXYGEN (FIO2)-HIGH FLOW NEBULIZER AND THE THERA MIST AIR ENTRAINMENT NEBULIZER IN DELIVERING HIGH OXYGEN CONCENTRATIONS FREE TO VIEW

Donna D. Gardner, RRT*; David L. Vines, RRT; Richard B. Wettstein, RRT; Juan Garcia, MD; Jay I. Peters, MD
Author and Funding Information

University of Texas Health Science Center at San Antonio, San Antonio, TX


Chest


Chest. 2005;128(4_MeetingAbstracts):305S-c-306S. doi:10.1378/chest.128.4_MeetingAbstracts.305S-c
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Abstract

PURPOSE:  Misty-Ox (MO)® nebulizer was developed to overcome shortcomings of conventional air-entrainment devices. The MISTY OX ® is designed to deliver FIO2s from 0.60 to 0.96 with total gas flows from 42 to 80 L/min. The THERA MIST® nebulizer is designed to deliver FIO2s from 0.36-0.96 with total gas flows from 47 to 74 L/min. We sought to determine the actual delivered FIO2 when using the MISTY OX® and the THERA MIST® via aerosol mask in normal subjects.

METHODS:  Following informed consent, 12 healthy volunteers, had a size 8 french nasal catheter (NC) inserted through one of the nares with the tip positioned at the level of the uvula. Subjects were placed on the THERA MIST® connected to large bore tubing and an aerosol mask. Oxygen therapy was then initiated at a set FIO2 of 0.60 at 15 L/min, then 0.80 and 0.95 at flush for a period of five minutes. The subjects were also placed on the Misty-Ox ® connected to large bore tubing and an aerosol mask. Oxygen therapy was then initiated at a set FIO2 of 0.65, 0.85 and 0.96 at 40 L/min flow using a high-flow flowmeter for a period of five minutes. With the subject breathing normally the gas was analyzed at three sites: the nebulizers’ outlet, the subjects’ lip and from the subjects’ pharynx. A previously calibrated oxygen analyzer measured the FIO2 of these samples. Three samples were obtained from each site, at each FIO2 setting and the mean and standard deviations were calculated.

RESULTS:  Means, standard deviations and ranges for the analyzed oxygen concentrations are included in the Table.

CONCLUSION:  Delivered FIO2 using the Thera Mist and the Misty Ox nebulizers can vary significantly from the set value. The delivered O2 can be 10 - 20 percent below the set value.

CLINICAL IMPLICATIONS:  Care should be taken when interpreting patients’ clinical response to oxygen therapy when using these devices. Patient may be receiving a FIO2 much less than anticipated based on the nebulizer setting. Analyzed FIO2 (SD) for High Oxygen Concentration Devices*DeviceThera MistMisty OxSet FIO2.0600.800.950.650.850.96Location of AnalysisNebulizer Outlet.53 (.03).74(.05).86(.05).64(.03).80(.03).86(.04)Subject’s Lip.56 (.04).72(.06).84(.05).63(.03).79(.04).84(.04)Oropharynx.47 (.03).65(.05).75(.06).56(.04).70(.06).73(.06)*

Mean (SD) of all subjects

DISCLOSURE:  Donna Gardner, None.

Wednesday, November 2, 2005

12:30 PM - 2:00 PM


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