The purpose of this study was to investigate the prevalence and prognosis of intrapulmonary shunts in patients with hepatic cirrhosis.
We investigated the prevalence and prognosis of intrapulmonary shunts in 82 patients (56 men and 26 women), mean age 54 years, with hepatic cirrhosis referred for contrast echocardiography as part of an evaluation for liver transplantation. Mean follow-up was 41 months in patients with intrapulmonary shunts and 42 months in patients without intrapulmonary shunts (p not significant).
Intrapulmonary shunts were present in 49 of 82 patients (60%) with hepatic cirrhosis. Baseline characteristics including the MELD score were not significantly different between patients with and without intrapulmonary shunts. At 41-month mean follow-up, 8 of 49 patients (16%) with intrapulmonary shunts and 4 of 33 patients (12%) without intrapulmonary shunts had died (p not significant).
Intrapulmonary shunts do not significantly increase mortality in patients with hepatic cirrhosis at long-term follow-up.
Patients with hepatic cirrhosis with and without intrapulmonary shunts have a similar mortality at long-term follow-up.
Manisha Das, None.