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Estimation of Mean Pulmonary Artery Pressure : Simpler Than Expected

Denis Chemla, MD; Philippe Hervé, MD
Author and Funding Information

Affiliations: Le Kremlin-Bicêtre, France ,  Le Plessis-Robinson, France

Correspondence to: Denis Chemla, MD, Service EFCR, Broca 7, Hôpital de Bicêtre, 78 rue du Général Leclerc, 94 275 Le Kremlin Bicêtre, Cedex, France; e-mail: denis.chemla@bct.ap-hop-paris.fr


Chest. 2008;133(3):592-593. doi:10.1378/chest.07-2718
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It is widely admitted that mean pulmonary artery pressure (mPAP) may be accurately estimated by using the standard formula: mPAP = 2/3 dPAP + 1/3 sPAP, where dPAP is diastolic pulmonary artery pressure, and sPAP is systolic pulmonary artery pressure. This rule of thumb implies that knowing the minimal and maximal values of the pressure signal allows a precise estimation of the mean pressure, as also documented at the systemic counterpart. Accordingly, it is admitted that mPAP is twice as sensitive to dPAP as it is to sPAP. The prominent role of dPAP in the formula implies that dPAP may reflect vascular tone more accurately than sPAP, which depends on pulmonary artery compliance, wave reflections, and characteristics of right ventricular ejection.

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