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Postgraduate Education Corner: CHEST IMAGING AND PATHOLOGY FOR CLINICIANS |

Unusual Dyspnea in a Woman With CREST Syndrome*

David Z. Tzeng, MD; Kevin O. Leslie, MD; David Shelton, MD; Andrew Chan, MBChB, FCCP
Author and Funding Information

*From Pulmonary and Critical Care Medicine (Drs. Tzeng and Chan) and Department of Radiology (Dr. Shelton), University of California Davis Medical Center, Sacramento, CA; and Department of Laboratory Medicine and Pathology (Dr. Leslie), Mayo Clinic, Scottsdale, AZ.

Correspondence to: David Z. Tzeng, MD, Clinical Fellow, Pulmonary and Critical Care Medicine, University of California Davis Medical Center, Sacramento, CA 95835; e-mail: david.tzeng@ucdmc.ucdavis.edu



Chest. 2008;133(1):286-290. doi:10.1378/chest.07-1211
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Extract

A 52-year-old female office worker, a lifelong nonsmoker, with a history of limited scleroderma associated with calcinosis, Raynaud phenomenon, sclerodactyly, and esophageal dysmotility was referred for evaluation of dyspnea. Limited scleroderma had been diagnosed 10 years previously, and she was without respiratory complaints until 2 months prior, when progressive dyspnea developed. Her rheumatoid factor was 29 U (normal 0 to 24 U) with an antinuclear antibody of 1:640 in a centromere pattern. Her anticentromere antibody was 1:5120.

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