A 44-year-old man with no medical history presented with multiple new-onset seizures during 1 week. He denied tobacco, alcohol, or illicit drug use. He worked for 15 years spraying pesticides and herbicides on farms. On presentation, the patient was actively seizing. He was treated with antiepileptic medications and intubated for airway protection.
RosenSHCastlemanBLiebowAAPulmonary alveolar proteinosisN Engl J Med19582582311231142ViroslavJWilliamsTWJrNocardial infection of the pulmonary and central nervous system: successful treatment with medical therapySouth Med J1971641113821385PrakashUBBarhamSSCarpenterHADinesDEMarshHMPulmonary alveolar phospholipoproteinosis: experience with 34 cases and a reviewMayo Clin Proc1987626499518HiguchiMKawaradaYNishioTTakiiMOkuboHA case of pulmonary alveolar proteinosis with increased IgE and CEA [in Japanese]Nihon Kyobu Shikkan Gakkai Zasshi1994323255260McNeilMMBrownJMThe medically important aerobic actinomycetes: epidemiology and microbiologyClin Microbiol Rev199473357417OerlemansWGJansenENPrevoRLEijsvogelMMPrimary cerebellar nocardiosis and alveolar proteinosisActa Neurol Scand1998972138141SeymourJFPresneillJJPulmonary alveolar proteinosis: progress in the first 44 yearsAm J Respir Crit Care Med20021662215235TrapnellBCWhitsettJANakataKPulmonary alveolar proteinosisN Engl J Med20033492625272539CostabelUNakataKPulmonary alveolar proteinosis associated with dust inhalation: not secondary but autoimmune?Am J Respir Crit Care Med20101815427428TazawaRTrapnellBCInoueYInhaled granulocyte/macrophage-colony stimulating factor as therapy for pulmonary alveolar proteinosisAm J Respir Crit Care Med20101811213451354