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Bronchiectasis in Patients With COPDBronchiectasis in COPD: A Distinct COPD Phenotype?

Anne E. O’Donnell, MD, FCCP
Author and Funding Information

From the Division of Pulmonary, Critical Care, and Sleep Medicine, Georgetown University Hospital.

Correspondence to: Anne E. O’Donnell, MD, FCCP, Division of Pulmonary, Critical Care, and Sleep Medicine, Georgetown University Hospital, 4 N Main Hospital, 3800 Reservoir Rd NW, Washington DC 20007; e-mail: odonnela@georgetown.edu


Financial/nonfinancial disclosures: The author has reported to CHEST the following conflicts of interest: Dr O’Donnell has received research funding for clinical trials from Bronchiectasis Registry/COPD Foundation; Gilead Sciences, Inc; Bayer Corporation; Pharmaxis, Inc; and Insmed Incorporated. She has received consultant fees from Gilead Sciences, Inc; Bayer Corporation; and Hill-Rom, Inc.

Reproduction of this article is prohibited without written permission from the American College of Chest Physicians (http://www.chestpubs.org/site/misc/reprints.xhtml).


© 2011 American College of Chest Physicians


Chest. 2011;140(5):1107-1108. doi:10.1378/chest.11-1484
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Due to the widespread and increasing use of high-resolution CT (HRCT) scanning in patients with pulmonary symptoms, bronchiectasis is increasingly being recognized across the spectrum of patients with chronic cough and dyspnea. Patients with idiopathic, postinfectious, congenital, and immunologically mediated “classic” bronchiectasis are relatively well characterized.1 In 2002, Barker described the overlapping and contrasting features between bronchiectasis and COPD.2 Both diseases are characterized by fixed airway obstruction and chronic cough. Bronchiectasis is usually due to a postinfectious or systemic disorder, is often complicated by gram-negative or mycobacterial infections, and is more common in women than men. COPD is due to cigarette smoking, is complicated by a variety of gram-positive and gram-negative bacterial infections, and occurs more often in men than women.

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