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Editorials |

Childhood AsthmaChildhood Asthma: A Whole-Child Approach: The Need for a Personalized “Whole Child” Approach

Lisa Cicutto, PhD, RN, APN
Author and Funding Information

From National Jewish Health and the Clinical Science Graduate Program, University of Colorado Denver.

Correspondence to: Lisa Cicutto, PhD, RN, APN, National Jewish Health, 1400 Jackson St, G08a, Denver, CO 80206; e-mail: cicuttol@njhealth.org


Financial/nonfinancial disclosures: The author has reported to CHEST that no potential conflicts of interest exist with any companies/organizations whose products or services may be discussed in this article.

Reproduction of this article is prohibited without written permission from the American College of Chest Physicians (http://www.chestpubs.org/site/misc/reprints.xhtml).


© 2011 American College of Chest Physicians


Chest. 2011;140(5):1108-1110. doi:10.1378/chest.11-1106
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Extract

Childhood asthma exerts a costly toll on individuals, families, and society. It is a complex and heterogeneous disease that consists of several clinical phenotypes. It is increasingly clear that this complex disease has numerous variants with differing underlying pathophysiologies. Asthma phenotyping directs attention at defining subgroups of asthma with distinct risk factors, comorbidities, triggers, and responses to treatment. To capture these diverse underlying pathophysiologies and their cognate mechanisms, the term “endotype” recently was suggested to define distinct mechanistic or pathophysiological subtypes of asthma.1,2 Currently, asthma phenotyping and endotyping are not part of the standard assessment, evaluation, and treatment of childhood asthma. As will become evident, this needs to change.

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