Financial/nonfinancial disclosures: The authors have reported to CHEST the following conflicts of interest: In the past 3 years, Dr Han has participated in advisory boards for Boehringer Ingelheim GmbH, Pfizer, GlaxoSmithKline, Genentech, Novartis, and Medimmune. She has participated on speaker’s bureaus for Boehringer Ingelheim GmbH, Pfizer, GlaxoSmithKline, the National Association for Continuing Education, and WebMD. She has consulted for Novartis and Nycomed, and has received royalties from UpToDate and ePocrates, Inc. In the past 3 years, Dr Dransfield has consulted for GlaxoSmithKline and Boehringer Ingelheim GmbH. His institution has received funds to conduct clinical research trials for GlaxoSmithKline and Boehringer Ingelheim GmbH. Over the past 3 years, Dr Make has participated in advisory boards, speaker bureaus, consultations, and multicenter clinical trials with funding from the National Heart, Lung, and Blood Institute; Abbott Laboratories; Astellas Pharma Inc; AstraZeneca; Boehringer Ingelheim GmbH; Dey Pharma, LP; Embryon Inc; Forest Laboratories, Inc; GlaxoSmithKline; Nabi Biopharmaceuticals; Nycomed; Novartis Pharmaceuticals Corporation; Pfizer Inc; Respironics Inc; Merck/Schering-Plough; SeQual Technologies; and Talecris Biotherapeutics, Inc. Dr Martinez has served on advisory boards relating to COPD-related topics for GlaxoSmithKline; MedImmune, LLC; AstraZeneca; Merck & Co, Inc; Pearl Therapeutics Inc, Novartis Pharmaceuticals Corporation, United BioSource Corporation; Forest Laboratories, Inc; and Almirall, SA. He has consulted for Actelion Pharmaceuticals Ltd; Boehringer Ingelheim GmbH; Nycomed; Forest Laboratories; F. Hoffmann-La Roche Ltd; Bayer Corporation, Merck/Schering-Plough; Health Learning Systems; Talecris Biotherapeutics, Inc; Comgenex; fb Communications; BoomComm; and Actelion Pharmaceuticals Ltd. He has served on speaker’s bureaus for GlaxoSmithKline; National Association for Continuing Education; Med-Ed; Potomac Center for Medical Education; Pfizer Inc; Boehringer Ingelheim GmbH; Merck/Schering-Plough; Vox Medica, Inc; American Lung Association; WebMD; ePocrates Inc; AstraZeneca; France Foundation; CME Incite; and Altana/Nycomed. His institution has received funds from Boehringer Ingelheim GmbH for a clinical trial. He has received royalties from Associates in Medical Marketing and Castle Connolly. He has developed educational materials for the France Foundation, HIT Global, and ePocrates Inc. He has served on steering committees for clinical trials supported by GlaxoSmithKline; Nycomed; Forest Laboratories, Inc; and Actelion Pharmaceuticals Ltd. Drs Curran-Everett, Criner, Zhang, Murphy, Hanzel, DeMeo, Regan, Westney, and Foreman have reported that no potential conflicts of interest exist with any companies/organizations whose products or services may be discussed in this article.