Dr Barbarito and colleagues also requested information on the total duration of mechanical ventilation. As they mention, the median duration of NIV use was longer with the ONM than the TFM, excluding the duration of use after switching to the alternative mask. However, when that duration is included, the total duration of NIV was similar. If, as Barbarito and colleagues request, we exclude those who discontinued early, the median duration of NIV tended to be shorter in the ONM group (23 h; interquartile range, 4.6-51.3; n=18) than in the TFM group (56.9 h; interquartile range, 15.7-98.4; n=12). The reason for these disparities is that more patients discontinued NIV early with a shorter duration of use in the TFM than the ONM group (n=16 vs 12, 0.7 vs 3.7 h), and patients using ONM were more apt to switch to the alternative mask (n=8 of 16 patients using TFM vs 0 of 12 patients using ONM, P < .05).