Human metapneumovirus (hMPV) is a newly described member of the Paramyxoviridae family. Along with human respiratory syncytial virus (hRSV) and influenza viruses, hMPV is one of the leading causes of acute respiratory tract infections (ARTIs).
Respiratory specimens collected from 60 hospitalized patients with lower respiratory tract infection (COPD, asthma, pneumonia, bronchiactesis) 15 patients for each group were screened for presence of metapneumovirus using real-time reverse transcription–polymerase chain reaction (RT-PCR).
Among these, 35 patients had a positive result for hMPV infection. hMPV accounted for 80% in COPD, 73.3% in bronchiactesis,60% pneumonic patients and 20% in asthma. Respiratory syncytial virus (RSV) was common a respiratory co-pathogen in these cases. hMPV positive cases had a longer duration of hospitalization, more days of oxygen use,and lower value of FEV1.
we found that hMPV is a relatively important viral pathogen that can lead to severe lower respiratory tract infections.
Human metapneumovirus should be considered in infective exacerbation of COPD, bronchial asthma, as well as lower respiratory tract infection such as pneumonia & bronchiactasis.
Amal Fathy, No Financial Disclosure Information; No Product/Research Disclosure Information