The true prevalence of mitral valve prolapse (MVP) in the population has been a controversy for many years. The goal of this study was to evaluate the prevalence of MVP and associated valvular abnormalities in healthy teenage students undergoing screening echocardiography across the United States and to evaluate for any gender differences.
The Anthony Bates Foundation has been performing screening echocardiography in high schools across the United States for the prevention of sudden death since 2002. A total of 2072 students were identified between the ages of 13 to 19 years. The prevalence of MVP and its associated valvular abnormalities were studied in this population.
Total prevalence of MVP was 0.7%. The prevalence of MVP was significantly higher among female teenage students [9/690, (1.3%) of female students vs. 5/1382 (0.4%) of male counterparts, p= 0.01, OR 3.6, CI 1.21–10.70]. The prevalence of all mitral (MR) and tricuspid (TR) regurgitations was higher in students with MVP whereas the prevalence of aortic regurgitation (AR) was similar in both groups. [MR occurred in 5/14 (35.7%) of students with MVP vs. in 15/2058 (0.7%) of controls, p< 0.001, OR 75.6 CI: 22.6–252.5, TR occurred in 1/14 of students with MVP vs. 9/2058, (0.4%) in controls, p<0.001, OR 17.5, CI: 2.0–148.3, AR occurred in 0/14, (0%) of students with MVP vs. 3/2058, (0.1%) of controls, p=0.8].
The prevalence of MVP in healthy teenage students is less than 1%. Furthermore, the prevalence of MVP is higher in female students and is markedly associated with very high prevalence of mitral and tricuspid regurgitations.
The prevalece of MVP is low in a population of young teenage students.
Sudhakar Sattur, No Financial Disclosure Information; No Product/Research Disclosure Information