Osteoporosis and osteopenia have high prevalence in patients with lung diseases. We report the prevalence of osteoporosis and osteopenia in a cohort of adult patients with non-CF bronchiectasis.
A database was constructed reviewing the electronic medical records of patients admitted to the hospital with acute exacerbation of bronchiectasis (3/1999 to 3/2009). We report demographics, rate of osteopenia and osteoporosis diagnosed with Dual Energy X-ray Absorptiometry (DEXA) Scan, history of smoking, body mass index, 25-hydroxy vitamin D levels and therapy with calcium, vitamin D and bisphosphonates.
A cohort of 113 patients was admitted during the study period. The mean age was 63, 76% were Caucasian and 70% were females. 59 (52%) patients had a DEXA scan of which 81% were females. 34 patients (30%) had osteopenia and 16 patients (14%) had osteoporosis. 47 (42%) patients had a history of smoking of which 57% were males. Mean body mass index was 23.7. Mean 25-hydroxy Vitamin D levels were 25.3 ng/mL. 67 patients (59%) were treated with calcium supplement and 45 patients (40%) with vitamin D.
The prevalence of osteopenia and osteoporosis is high in patients with non-CF bronchiectasis.
A systematic approach looking for osteoporosis and osteopenia may be indicated in patients with non-CF bronchiectasis.
Rupesh Dave, No Financial Disclosure Information; No Product/Research Disclosure Information