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Abstract: Poster Presentations |

ENDOBRONCHIAL ULTRASOUND-GUIDED TRANSBRONCHIAL NEEDLE ASPIRATION IN THE DIAGNOSIS OF LUNG CANCER FREE TO VIEW

Jeong Eun Lee; Bin Hwangbo
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Chungnam National University Hospital and Cancer Research Institute, Daejeon, South Korea


Chest


Chest. 2009;136(4_MeetingAbstracts):111S. doi:10.1378/chest.08-1901
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Abstract

PURPOSE:  Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) is a promising method in the mediastinal staging of non-small cell lung cancer (NSCLC). However, the role of EBUS-TBNA in the diagnosis of lung cancer has not been well studied.

METHODS:  We retrospectively reviewed 126 patients who underwent EBUS-TBNA in order to diagnose radiologically suspected lung cancer from June, 2006 to February, 2009. The patients had EBUS-TBNA accessible masses or lymph nodes that were highly suspicious for malignancy.

RESULTS:  EBUS-TBNA was performed on 195 lesions (126 mediastinal nodes, 24 hilar nodes, 44 lung masses & 1 mediastinal mass) in 126 patients without complications. EBUS-TBNA confirmed 110 malignant cases (91 NSCLC, 15 small cell lung cancer, 3 metastatic lung cancer & 1 lymphoma) and 6 benign cases (1 adenoma, 3 tuberculosis, 1 sarcoidosis & 1 aspregillosis). The overall diagnostic yield of EBUS-TBNA was 92.1% (116/126). Nine of the 10 cases that were not confirmed to be malignant or to have specific benign disease by EBUS-TBNA were diagnosed by other methods (2 NSCLC, 1 Castleman's disease, 1 lymphoma, 1 hamartoma, 1 tuberculosis & 3 pneumonia). One case not confirmed by any diagnostic method was considered to be false negative. The sensitivity and diagnostic accuracy of EBUS-TBNA in the diagnosis of malignancy were 95.7% (110/115) and 96.0% (121/126), respectively. Those values in the diagnosis of lung cancer were 97.2% (106/109) and 97.6% (123/126), respectively.

CONCLUSION:  EBUS-TBNA showed high diagnostic values in the diagnosis of lung cancer when EBUS-TBNA accessible masses or lymph nodes that were highly suspicious for malignancy were noted. EBUS-TBNA is recommendable for these patients.

CLINICAL IMPLICATIONS:  The role of EBUS-TBNA in the diagnosis of lung cancer.

DISCLOSURE:  Jeong Eun Lee, No Financial Disclosure Information; No Product/Research Disclosure Information

Wednesday, November 4, 2009

12:45 PM - 2:00 PM


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